ISSN:
1572-8773
Keywords:
Iron availability
;
Microbial pathogenicity
;
Iron-uptake system
;
Haem
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Chemistry and Pharmacology
Notes:
Summary Iron is now recognized as playing a vital role in infection. Not only does its restricted availability in tissue fluids present microbial pathogens with the problem of acquiring sufficient for multiplication in vivo, but it also constitutes a major environmental signal which co-ordinately regulates the expression of a number of virulence and metabolic genes. Progress in understanding the strategies used by pathogens for acquiring iron in vivo, and their responses to iron restriction, is providing a fresh insight into microbial pathogenicity.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01135551
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