ALBERT — All Library Books, journals and Electronic Records Telegrafenberg

Hits per page

hits 1 - 2 | 2 hits

Sorting

Electronic Resource

The l-histidine-mediated enhancement of hydrogen peroxide-induced cytotoxicity is a general response in cultured mammalian cell lines and is always associated with the formation of DNA double strand breaks

Cantoni, O. ; Sestili, P. ; Brandi, G. ; [et al.]

Amsterdam : Elsevier

FEBS Letters 353 (1994), S. 75-78

add to mindlist on the mindlist

Details

ISSN: 0014-5793

Keywords: Cytotoxicity ; DNA double strand breaks ; Hydrogen peroxide ; l-Histidine

Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002

Topics: Biology , Chemistry and Pharmacology , Physics

Type of Medium: Electronic Resource

URL: http://linkinghub.elsevier.com/retrieve/pii/0014-5793(94)01010-2

Permalink

	Location	Call Number	Expected	Availability

Others were also interested in ...

Paper (German National Licenses)

Fulltext

Electronic Resource

Comparison of Quantitative Calcaneal Ultrasound and Dual Energy X-ray Absorptiometry in the Evaluation of Osteoporotic Risk in Children with Chronic Rheumatic Diseases (2000)

Falcini, F. ; Bindi, G. ; Ermini, M. ; [et al.]

Springer

Calcified tissue international 67 (2000), S. 19-23

add to mindlist on the mindlist

Details

ISSN: 1432-0827

Keywords: Key words: Broadband ultrasound attenuation — Contact ultrasound bone analyzer — Bone mineral density — Dual energy X-ray absorptiometry — Chronic rheumatic diseases.

Source: Springer Online Journal Archives 1860-2000

Topics: Biology , Medicine , Physics

Notes: Abstract. Osteoporosis is a common complication in children with chronic rheumatic diseases (CRD). Although dual energy X-ray absorptiometry (DXA) is increasingly being used to determine bone mineral density (BMD) in children, it exposes the subject to ionizing radiation and does not provide a measure of true bone density; in fact, in growing bones the increase in BMD is mainly caused by the increase in bone size. In recent years, quantitative ultrasound techniques (QUS) have been used in radiation-free assessment of bone density and ``bone quality'' by measurement of the ultrasound waves attenuation by bone (BUA). In the present study we made a direct comparison of BUA in the calcaneum, determined by the pediatric contact ultrasound bone analyzer (CUBA) with lumbar BMD measured by DXA, in a group of 6–18-year-old patients with CRD. The study group consisted of 53 patients affected with juvenile rheumatoid arthritis (n = 29), systemic lupus erythematosus (n = 13), and juvenile dermatomyositis (n = 11). Mean age was 13.02 ± 2.69 years. In 22 patients (19 girls, 3 boys) both DXA and CUBA were repeated after 1 year in order to assess the mean percentage rate of BMD and BUA change over this time. Both lumbar spine BMD and calcaneal BUA measurements were lower in the CRD patients compared with a control group (P 〈 0.001). Calcaneal BUA was significantly correlated (r = 0.83, P 〈 0.001) with lumbar spine BMD. Age and sex correction (Z-score) did not change the relationship between BUA and BMD (r = 0.80, P 〈 0.001). A significant correlation between the mean percentage of variation (Δ%) of BMD and BUA (r = 0.76, P 〈 0.001) was also demonstrated in the 22 patients who were evaluated prospectively. Portability, ease of use, lower cost, and absence of radiation make CUBA a promising means of evaluating BMD in children.