ALBERT

All Library Books, journals and Electronic Records Telegrafenberg

feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Publication Date: 1988-09-16
    Description: Alzheimer's disease is the most common form of dementia among the elderly population. Although the etiology is unknown, inheritance plays a role in the pathogenesis of the disease. Recent work indicates that an autosomal dominant gene for Alzheimer's disease is located on chromosome 21 at band q21. In the present study of a group of autopsy-documented kindreds, no evidence for linkage was found between familial Alzheimer's disease (FAD) and chromosome 21q21 markers (D21S1/D21S72 and the amyloid beta gene). Linkage to the D21S1/D21S72 locus was excluded at recombination fractions (theta) up to 0.17. Linkage to the amyloid gene was excluded at theta = 0.10. Apparent recombinants were noted in two families for the amyloid gene and in five families for the D21S1/D21S72 locus. These data indicate that FAD is genetically heterogeneous.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Schellenberg, G D -- Bird, T D -- Wijsman, E M -- Moore, D K -- Boehnke, M -- Bryant, E M -- Lampe, T H -- Nochlin, D -- Sumi, S M -- Deeb, S S -- AG 00057/AG/NIA NIH HHS/ -- AG 05136/AG/NIA NIH HHS/ -- GM 15253/GM/NIGMS NIH HHS/ -- New York, N.Y. -- Science. 1988 Sep 16;241(4872):1507-10.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Division of Neurology, University of Washington, Seattle 98195.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/3420406" target="_blank"〉PubMed〈/a〉
    Keywords: Alzheimer Disease/*genetics ; Chromosome Mapping ; *Chromosomes, Human, Pair 21 ; Genetic Linkage ; Humans
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 2
    Publication Date: 2014-10-25
    Description: Study of human adaptation to extreme environments is important for understanding our cultural and genetic capacity for survival. The Pucuncho Basin in the southern Peruvian Andes contains the highest-altitude Pleistocene archaeological sites yet identified in the world, about 900 meters above confidently dated contemporary sites. The Pucuncho workshop site [4355 meters above sea level (masl)] includes two fishtail projectile points, which date to about 12.8 to 11.5 thousand years ago (ka). Cuncaicha rock shelter (4480 masl) has a robust, well-preserved, and well-dated occupation sequence spanning the past 12.4 thousand years (ky), with 21 dates older than 11.5 ka. Our results demonstrate that despite cold temperatures and low-oxygen conditions, hunter-gatherers colonized extreme high-altitude Andean environments in the Terminal Pleistocene, within about 2 ky of the initial entry of humans to South America.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Rademaker, Kurt -- Hodgins, Gregory -- Moore, Katherine -- Zarrillo, Sonia -- Miller, Christopher -- Bromley, Gordon R M -- Leach, Peter -- Reid, David A -- Alvarez, Willy Yepez -- Sandweiss, Daniel H -- New York, N.Y. -- Science. 2014 Oct 24;346(6208):466-9. doi: 10.1126/science.1258260.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Anthropology, South Stevens Hall, University of Maine, Orono, ME 04469-5773, USA. Department of Early Prehistory and Quaternary Ecology, Schloss Hohentubingen, Burgsteige 11, 72070 Tubingen, Germany. Climate Change Institute, Bryand Global Sciences Center, University of Maine, Orono, ME 04469, USA. kurt.rademaker@umit.maine.edu. ; Accelerator Mass Spectrometry Laboratory, Department of Physics and School of Anthropology, University of Arizona, Tucson, AZ 85721, USA. ; University of Pennsylvania Museum, 3260 South Street, Philadelphia, PA 19104, USA. ; Department of Anthropology and Archaeology, Earth Sciences Building, Room 806, 844 Campus Place Northwest, Calgary, British Columbia, Canada. ; Institute for Archaeological Sciences, University of Tubingen, Rumelinstrasse 23, 72070 Tubingen, Germany. Senckenberg Centre for Human Evolution and Paleoenvironment, University of Tubingen, Rumelinstrasse 23, 72070 Tubingen, Germany. ; Climate Change Institute, Bryand Global Sciences Center, University of Maine, Orono, ME 04469, USA. ; Department of Anthropology, 354 Mansfield Road, University of Connecticut, Storrs, CT 06269-1176, USA. ; Department of Anthropology, University of Illinois at Chicago, Behavioral Sciences Building, 1007 West Harrison Street, Chicago, IL 60607-7139, USA. ; Arequipa, Peru. ; Department of Anthropology, South Stevens Hall, University of Maine, Orono, ME 04469-5773, USA. Climate Change Institute, Bryand Global Sciences Center, University of Maine, Orono, ME 04469, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/25342802" target="_blank"〉PubMed〈/a〉
    Keywords: *Acclimatization ; *Altitude ; Archaeology ; Artifacts ; Humans ; Peru
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 3
    facet.materialart.
    Unknown
    American Association for the Advancement of Science (AAAS)
    Publication Date: 1980-02-22
    Description: A technique for bypassing the eyelids permits equivalent visual stimulation of the retina before, during, or after a blink. Sensitivity to these stimuli decreases during voluntary blinks. This indicates that the source of the deficit is neural rather than optical. Such a visual loss may help to explain the common experience that most blinks go unnoticed.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Volkmann, F C -- Riggs, L A -- Moore, R K -- New York, N.Y. -- Science. 1980 Feb 22;207(4433):900-2.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7355270" target="_blank"〉PubMed〈/a〉
    Keywords: Brain/physiology ; Eye Movements ; Eyelids/*physiology ; Humans ; Retina/physiology ; Visual Perception/*physiology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 4
    facet.materialart.
    Unknown
    American Association for the Advancement of Science (AAAS)
    Publication Date: 1979-07-13
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Meltzoff, A N -- Moore, M K -- New York, N.Y. -- Science. 1979 Jul 13;205(4402):217-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/451596" target="_blank"〉PubMed〈/a〉
    Keywords: Behavior/*physiology ; Fingers/physiology ; Humans ; *Infant, Newborn ; Methods ; Reflex/physiology ; Tongue/physiology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...