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  • 1
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    Assessment of pharmacological treatment of myocardial infarction by phosphorus-31 NMR with surface coils (1981)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1981-01-09
    Description: Phosphorus-31 nuclear magnetic resonance (NMR) measurements with small surface coils have been used to observe phosphorus metabolism of perfused hearts within localized regions. The method allows for direct, noninvasive, sequential assessment of the altered regional metabolism resulting from myocardial infarction and its response to drug treatment, which cannot be observed by conventional techniques.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Nunnally, R L -- Bottomley, P A -- GM 17172/GM/NIGMS NIH HHS/ -- HL 17655-06/HL/NHLBI NIH HHS/ -- HL 22080/HL/NHLBI NIH HHS/ -- New York, N.Y. -- Science. 1981 Jan 9;211(4478):177-80.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7444460" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Chlorpromazine/therapeutic use ; Coronary Circulation/drug effects ; Disease Models, Animal ; Magnetic Resonance Spectroscopy/*methods ; Myocardial Infarction/*diagnosis/drug therapy/metabolism ; Phosphorus/*metabolism ; Phosphorus Isotopes ; Rabbits ; Verapamil/therapeutic use
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 2
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    Noninvasive study of high-energy phosphate metabolism in human heart by depth-resolved 31P NMR spectroscopy (1985)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1985-08-23
    Description: Phosphorus-31 nuclear magnetic resonance (NMR) spectra showing the relative concentrations of high-energy phosphate metabolites have been recorded noninvasively from the human heart in vivo. Spectral data were spatially localized by combining a pulsed magnetic field gradient with surface NMR excitation-detection coils. The location of the selected spectral region was determined by conventional proton NMR imaging immediately before examination by phosphorus-31 NMR spectroscopy.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Bottomley, P A -- New York, N.Y. -- Science. 1985 Aug 23;229(4715):769-72.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/4023711" target="_blank"〉PubMed〈/a〉
    Keywords: Adenine Nucleotides/metabolism ; Energy Metabolism ; Humans ; Magnetic Resonance Spectroscopy ; Myocardium/*metabolism ; Phosphates/*metabolism ; Phosphocreatine/metabolism
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
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