ISSN:
1617-4623
Keywords:
Pseudomonas aeruginosa
;
Heterologous gene expression
;
Phosphate regulation
;
Alkaline phosphatase
;
Complementation
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
Notes:
Summary In Pseudomonas aeruginosa, phosphate limitation results in the synthesis of several protein species. We report the cloning of the P. aeruginosa alkaline phosphatase structural gene, phoA, and we show that this gene is regulated normally in Escherichia coli. We have also identified and cloned two P. aeruginosa genes which can complement phoB and phoR mutations in E. coli. This suggests that a pho regulon system similar to that in E. coli may exist in P. aeruginosa, using at least two similar regulatory factors.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00330857
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