ISSN:
1573-904X
Keywords:
HMG-CoA reductase inhibitor
;
SQ-33600
;
crystal structure
;
hydrates
;
solid-state fluorescence
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Abstract It has been shown previously that the disodium salt of a new HMG-CoA reductase inhibitor (SQ-33600) is capable of existing as a number of hydrate species [1]. Three crystalline solid hydrates and one liquid crystalline phase have been identified, each having a definite stability over a defined range of humidity. These forms have been found to exhibit varying fluorescence properties in their respective solid states, with differences in bandshapes and intensities being noted for each. These spectral variations have been correlated with the known pseudopolymorphism of the compound.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1023/A:1016206130213
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