Publication Date:
2000-09-16
Description:
Language-relevant processing of auditory signals is lateralized and involves the posterior part of Brodmann area 22. We found that the functional lateralization in this area was accompanied by interhemispheric differences in the organization of the intrinsic microcircuitry. Neuronal tract tracing revealed a modular network of long-range intrinsic connections linking regularly spaced clusters of neurons. Although the cluster diameter was similar in both hemispheres, their spacing was about 20 percent larger in the left hemisphere. Assuming similar relations between functional and anatomical architecture as in visual cortex, the present data suggest that more functionally distinct columnar systems are included per surface unit in the left than in the right area 22.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Galuske, R A -- Schlote, W -- Bratzke, H -- Singer, W -- New York, N.Y. -- Science. 2000 Sep 15;289(5486):1946-9.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Neurophysiology, Max-Planck-Institute for Brain Research, Deutschordenstrasse 46, 60528 Frankfurt a.M., Germany. galuske@mpih-frankfurt.mpg.de〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/10988077" target="_blank"〉PubMed〈/a〉
Keywords:
Adult
;
Aged
;
Aged, 80 and over
;
Auditory Cortex/anatomy & histology/physiology
;
*Brain Mapping
;
Carbocyanines
;
Female
;
Fluorescent Dyes
;
Humans
;
Male
;
Middle Aged
;
Neural Pathways
;
Temporal Lobe/*anatomy & histology/physiology
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
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