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The relationship between coding sequences and function in some heme binding proteins (1980)

Argos, Patrick ; Rossmann, Michael G.

Springer

Journal of molecular evolution 16 (1980), S. 149-150

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ISSN: 1432-1432

Keywords: Exons ; Evolution ; Heme-binding proteins

Source: Springer Online Journal Archives 1860-2000

Topics: Biology

Notes: Summary It is known that globin genes contain three exons with the middle exon coding for a four-helical supersecondary structure responsible for heme binding. Since this portion of the globin peptide chain can be structurally superimposed onto the cytochromec and cytochromeb 5 chains (Argos and Rossmann 1979), it can be inferred that the cytochromec gene will contain only one coding sequence while the cytochromeb 5 gene will be composed of three exons as found in the globin gene.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF01731583

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