ISSN:
1432-1432
Keywords:
Evolutionary trees
;
Base composition
;
Transversional equilibrium
;
Endosymbiont hypothesis
;
Statistical testing
;
RNA polymerase
;
Archaebacteria
;
Eubacteria
;
Eukaryotes
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
Notes:
Summary We present compositional statistics, a new method of phylogenetic inference, which is an extension of evolutionary parsimony. Compositional statistics takes account of the base composition of the compared sequences by using nucleotide positions that evolutionary parsimony ignores. It shares with evolutionary parsimony the features of rate invariance and the fundamental distinction between transitions and transversions. Of the presently available methods of phylogenetic inference, compositional statistics is based on the fewest and mildest assumptions about the mode of DNA sequence evolution. It is therefore applicable to phylogenetic studies of the most distantly related organisms or molecules. This was illustrated by analyzing conservative positions in the DNA sequences of the large subunit of RNA polymerase from three archaebacterial groups, a eubacterium, a chloroplast, and the three eukaryotic polymerases. Internally consistent results, which are in accord with our knowledge of organelle origin and archaebacterial physiology, were achieved.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02101792
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