ISSN:
1420-9071
Schlagwort(e):
Enzyme inhibitors
;
biomimetic chemistry
;
chemically modified enzymes
;
catalytic antibodies
Quelle:
Springer Online Journal Archives 1860-2000
Thema:
Biologie
,
Medizin
Notizen:
Abstract Molecular recognition impinges upon many fields of biological chemistry, especially those involving catalytic processes. This review gives examples from studies at Strathclyde of both small and macromolecular systems. Mechanism-based enzyme inhibitors are described with reference to dihydrofolate reductase, dihydroorotate dehydrogenase, and cholesterol metabolism. Applications of molecular recognition related to synthetic transformations are discussed in terms of aromatic substitution, chemically modified papain, and catalytic antibodies for Diels-Alder reactions.
Materialart:
Digitale Medien
URL:
http://dx.doi.org/10.1007/BF01918378
Permalink
