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  • Engineering (General)  (3)
  • Polymer and Materials Science  (2)
  • 1
    Electronic Resource
    Electronic Resource
    The healing of hamster skin ulcers treated with n-butyl-2-cyanoacrylate (Histoacryl blue) (1984)
    Hoboken, NJ : Wiley-Blackwell
    Journal of Biomedical Materials Research 18 (1984), S. 601-607 
    Details
    ISSN: 0021-9304
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine , Technology
    Notes: This study was undertaken to examine the effectiveness of a commercially available n-butyl-2-cyanoacrylate (Histoacryl blueTri-Hawk International, 1570 Barré, Montréal, H4L 4M6 Quebec.) as a local treatment for cutaneous ulcers. Two ulcers, approximately 0.5 cm2 each, were made on the backs of 30 hamsters. The right side was covered with a thin film of tissue adhesive, while the left side was left untreated as a control. Animals were sacrificed at various times post-operatively, the tissue excised, processed, and examined with the light microscope. Results showed that cyanoacrylate decreased the inflammatory exudate early in the experiment, and epithelial migration occurred slightly earlier in experimental tissue. Scab formation was absent in experimental sites until the layer of adhesive was lost. After 2 days, healing was comparable in both experimental and control, and the sites were indistinguishable histologically at day 5.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jbm.820180602
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    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Detection of cyanoacrylate tissue adhesives in histological sections (1984)
    Hoboken, NJ : Wiley-Blackwell
    Journal of Biomedical Materials Research 18 (1984), S. 609-616 
    Details
    ISSN: 0021-9304
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine , Technology
    Notes: Previous histological studies of cyanoacrylate in wound healing have all used Oil-Red-O staining of paraffin sections prepared by routine method. In the course of our studies we began to suspect that artifact was being introduced because of dissolution of cyanoacrylate during processing. Accordingly, biopsis of wounds sealed with cyanoacrylate and pieces of cyanoacrylate of a standard known dimension with no associated tissue were observed after every stage of histological preparation. It was observed that approximately 80% of the cyanoacrylate was lost at the deparaffinization in xylene stage. Accordingly, a number of solvents were tested, and it was found that petroleum ether could be used to remove paraffin completely without the loss of any of the cyanoacrylate from the specimen. This technique has been used to view the location and ultimate fate of cyanoacrylate applied to wounds and examined at different stages in healing process. It is concluded that previous histological studies of cyanoacrylate in wound healing have been inaccurate due to leaching out of most of the tissue adhesive during deparaffinization of the specimen.
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jbm.820180603
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    Paper (German National Licenses)
    Fulltext
  • 3
    facet.materialart.
    Unknown
    Superpolishing and Precision Metrology on a Metal Mandrel and Replicated Segments for Constellation-X (1999)
    In:  Other Sources
    Details
    Publication Date: 2019-07-13
    Description: We have superpolished a diamond-turned aluminum mandrel (coated with electroless Ni) to an axial roughness of 0.34 nm rms. The mandrel is made to the Astro-E secondary mirror design for the 81st shell. Precision metrology at 100 mm to submicron scales has established the power spectral density of the mandrel and ultralightweight gold coated replicated segments. Predicted image quality of a set of optimally aligned replicated segments of this and a matching primary is substantially improved as compared to the flight mirrors for Astro-E. This approach using metal mandrels, superpolishing, and replicated ultralightweight foil mirrors, may represent a cost-effective approach to meeting the 15 arcsec half-energy width and weight requirements for the Constellation-X mission. Descriptions of the polishing apparatus, the precision metrology instruments, and the surface data analysis are presented. The general methods described are applicable to precision optics for both normal incidence and grazing incidence optics.
    Keywords: Engineering (General)
    Type: Jul 01, 1999; Unknown
    Format: text
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    NASA TECHNICAL REPORTS
  • 4
    facet.materialart.
    Unknown
    Superpolishing and Precision Metrology on a Metal Mandrel and Replicated Segments for Constellation-X (1999)
    In:  Other Sources
    Details
    Publication Date: 2019-07-17
    Description: We have superpolished a diamond-turned aluminum mandrel (coated with electroless Ni) to an axial roughness of 0.34 nm rms. The mandrel is made to the Astro-E secondary mirror design for the 81st shell. Precision metrology at 100 mm to submicron scales has established the power spectral density of the mandrel and ultralightweight gold coated replicated segments. Predicted image quality of a set of optimally aligned replicated segments of this and a matching primary is substantially improved as compared to the flight mirrors for Astro-E. This approach using metal mandrels, superpolishing, and replicated ultralightweight foil mirrors, may represent a cost-effective approach to meeting the 15 arcsec half-energy width and weight requirements for the Constellation-X mission. Descriptions of the polishing apparatus, the precision metrology instruments, and the surface data analysis are presented. The general methods described are applicable to precision optics for both normal incidence and grazing incidence optics.
    Keywords: Engineering (General)
    Type: SPIE Conference; Jul 01, 1999; United States
    Format: text
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    NASA TECHNICAL REPORTS
  • 5
    facet.materialart.
    Unknown
    Superpolishing and Precision Metrology on a Metal Mandrel and Replicated Segments for Constellation-X (1999)
    In:  Other Sources
    Details
    Publication Date: 2019-07-13
    Description: We have superpolished a diamond-turned aluminum mandrel (coated with electroless Ni) to an axial roughness of 6.34 nm rms. The mandrel is made to the Astro-E secondary mirror design for the 81st shell. Precision metrology at 100 mm to submicron scales has established the power spectral density of the mandrel and ultralightweight gold coated replicated segments. Predicted image quality of a set of optimally aligned replicated segments of this and a matching primary is substantially improved as compared to the flight mirrors for Astro-E. This approach using metal mandrels, superpolishing, and replicated ultralightweight foil mirrors, may represent a cost-effective approach to meeting the 15 arcsec half-energy width and weight requirements for the Constellation-X mission. Descriptions of the polishing apparatus, the precision metrology instruments, and the surface data analysis are presented. The general methods described are applicable to precision optics for both normal incidence and grazing incidence optics.
    Keywords: Engineering (General)
    Type: Jul 01, 1999; Unknown
    Format: text
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    NASA TECHNICAL REPORTS
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