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  • 1
    Electronic Resource
    Electronic Resource
    Cathepsin B synthesis by the HL60 promyelocytic cell line: effects of stimulating agents and anti-inflammatory compounds
    Amsterdam : Elsevier
    Biochimica et Biophysica Acta (BBA)/Molecular Cell Research 887 (1986), S. 283-290 
    Details
    ISSN: 0167-4889
    Keywords: (Promyelocyte) ; Anti-inflammatory agent ; Cathepsin B ; Cysteine proteinase ; Endotoxin
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Medicine , Physics
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0167-4889(86)90156-4
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    Paper (German National Licenses)
    Fulltext
  • 2
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    Genesis Solar-Wind Sample Return Mission: The Materials (2003)
    In:  CASI
    Details
    Publication Date: 2017-10-02
    Description: The Genesis spacecraft has two primary instruments which passively collect solar wind. The first is the collector arrays , a set of panels, each of which can deploy separately to sample the different kinds of solar wind (regimes). The second is the concentrator, an electrostatic mirror which will concentrate ions of mass 4 through mass 25 by about a factor of 20 by focusing them onto a 6 cm diameter target. When not deployed, these instruments fit into a compact canister. After a two year exposure time, the deployed instruments can be folded up, sealed into the canister, and returned to earth for laboratory analysis. Both the collector arrays and the concentrator will contain suites of ultra-high purity target materials, each of which is tailored to enable the analysis of a different family of elements. This abstract is meant to give a brief overview of the Genesis mission, insight into what materials were chosen for flight and why, as well as head s up information as to what will be available to planetary scientist for analysis when the solar-wind samples return to Earth in 2003. Earth. The elemental and isotopic abundances of the solar wind will be analyzed in state-of-the-art laboratories, and a portion of the sample will be archived for the use of future generations of planetary scientists. Technical information about the mission can be found at www.gps.caltech.edu/genesis.
    Keywords: Solar Physics
    Type: Lunar and Planetary Science XXXI; United States|Space Science Reference Guide, 2nd Edition; LPI-Contrib-1154
    Format: text
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    NASA TECHNICAL REPORTS
  • 3
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    Genesis: Sorting Out the Pieces (2005)
    In:  CASI
    Details
    Publication Date: 2017-10-02
    Description: The Genesis mission returned to Earth on September 8, 2004, experiencing a non-nominal reentry. The parachutes which were supposed to slow and stabilize the capsule throughout the return failed to deploy, causing the capsule to impact the desert floor at a speed of nearly 200 MPH. The result is that instead of receiving 301 intact solar wind collectors, mission personnel recovered and documented more than 10,000 collector fragments. Most of the fragments were pieces of the collector arrays but were not recovered on their original array locations. These were classified by size (longest dimension), identity (sometimes a guess) and found location (when known). The work took more than one month in Utah, and details are discussed elsewhere[1] The samples were transferred to their permanent home at the Johnson Space Center on October 4, 2004.
    Keywords: Solar Physics
    Type: Lunar and Planetary Science XXXVI, Part 13; LPI-Contrib-1234-Pt-13
    Format: application/pdf
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    NASA TECHNICAL REPORTS
  • 4
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    The Genesis Mission Solar Wind Collection: Solar-Wind Statistics over the Period of Collection (2004)
    In:  CASI
    Details
    Publication Date: 2018-06-11
    Description: The NASA Genesis spacecraft was launched August 8, 2001 on a mission to collect samples of solar wind for 2 years and return them to earth September 8, 2004. Detailed analyses of the solar wind ions implanted into high-purity collection substrates will be carried out using various mass spectrometry techniques. These analyses are expected to determine key isotopic ratios and elemental abundances in the solar wind, and by extension, in the solar photosphere. Further, the photospheric composition is thought to be representative of the solar nebula with a few exceptions, so that the Genesis mission will provide a baseline for the average solar nebula composition with which to compare present-day compositions of planets, meteorites, and asteroids. The collection of solar wind samples is almost complete. Collection began for most substrates in early December, 2001, and is scheduled to be complete on April 2 of this year. It is critical to understand the solar-wind conditions during the collection phase of the mission. For this reason, plasma ion and electron spectrometers are continuously monitoring the solar wind proton density, velocity, temperature, the alpha/proton ratio, and angular distribution of suprathermal electrons. Here we report on the solar-wind conditions as observed by these in-situ instruments during the first half of the collection phase of the mission, from December, 2001 to present.
    Keywords: Solar Physics
    Type: Lunar and Planetary Science XXXV: Genesis Mission; LPI-Contrib-1197
    Format: text
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    NASA TECHNICAL REPORTS
  • 5
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    Genesis Solar Wind Collector Cleaning Assessment: Update on 60336 Sample Case Study (2015)
    In:  CASI
    Details
    Publication Date: 2019-07-13
    Description: To maximize the scientific return of Genesis Solar Wind return mission it is necessary to characterize and remove a crash-derived particle and thin film surface contamination. A small subset of Genesis mission collector fragments are being subjected to extensive study via various techniques. Here we present an update on the sample 60336, a Czochralski silicon (Si-CZ) based wafer from the bulk array (B/C). This sample has undergone multiple cleaning steps (see the table below): UPW spin wash, aggressive chemical cleanings (including aqua regia, hot xylene and RCA1), as well as optical and chemical (EDS, ToF-SIMS) imaging. Contamination appeared on the surface of 60336 after the initial 2007 UPW cleaning. Aqua regia and hot xylene treatment (8/13/2013) did little to remove contaminants. The sample was UPW cleaned for the third time and imaged (9/16/13). The UPW removed the dark stains that were visible on the sample. However, some features, like "the Flounder" (a large, 100 micron feature in Fig. 1b) appeared largely intact, resisting all previous cleaning efforts. These features were likely from mobilized adhesive, derived from the Post-It notes used to stabilize samples for transport from Utah after the hard landing. To remove this contamination, an RCA step 1 organic cleaning (RCA1) was employed. Although we are still uncertain on the nature of the Flounder and why it is resistant to UPW and aqua regia/hot xylene treatment, we have found RCA1 to be suitable for its removal. It is likely that the glue from sticky pads used during collector recovery may have been a source for resistant organic contamination [9]; however [8] shows that UPW reaction with crash-derived organic contamination does not make particle removal more difficult.
    Keywords: Solar Physics
    Type: JSC-CN-32716 , Lunar and Planetary Science Conference; Mar 16, 2015 - Mar 20, 2015; The Woodlands, TX; United States
    Format: application/pdf
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    NASA TECHNICAL REPORTS
  • 6
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    Cellulose Acetate Replica Cleaning Study of Genesis Non-Flight Sample 3CZ00327 (2014)
    In:  CASI
    Details
    Publication Date: 2019-07-13
    Description: The Genesis mission collected solar wind and brought it back to Earth in order to provide precise knowledge of solar isotopic and elemental compositions. The ions in the solar wind were stopped in the collectors at depths on the order of 10 to a few hundred nanometers. This shallow implantation layer is critical for scientific analysis of the composition of the solar wind and must be preserved throughout sample handling, cleaning, processing, distribution, preparation and analysis. We are working interactively with the community of scientists analyzing Genesis samples, using our unique laboratory facilities -- and, where needed, our unique cleaning techniques -- to significantly enhance the science return from the Genesis mission. This work is motivated by the need to understand the submicron contamination on the collectors in the Genesis payload as recovered from the crash site in the Utah desert, and -- perhaps more importantly -- how to remove it. That is, we are evaluating the effectiveness of the wet-chemical "cleaning" steps used by various investigators, to enable them to design improved methods of stripping terrestrial contamination from surfaces while still leaving the solar-wind signal intact.
    Keywords: Solar Physics
    Type: JSC-CN-30432 , Lunar and Planetary Science Conference; Mar 17, 2014 - Mar 21, 2014; The Woodlands, TX; United States
    Format: application/pdf
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    NASA TECHNICAL REPORTS
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