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Evidence for a blood-bursa barrier (1985)

Davenport, W. D. ; Allen, E. R.

Springer

Cell & tissue research 240 (1985), S. 251-253

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ISSN: 1432-0878

Keywords: Endothelium ; Bursa of Fabricius ; Permeability ; Horseradish peroxidase ; Microvasculature ; Chicken

Source: Springer Online Journal Archives 1860-2000

Topics: Biology , Medicine

Notes: Summary By use of horseradish peroxidase (Sigma Type II) as a vascular tracer the competence of the bursal microvasculature was evaluated in 15-day-old chicks. Within 5 min circulation time tracer could by identified only within the vascular tree with no leakage into the perivascular or extracellular spaces. After 10 min circulation time tracer was no longer present in the bursal vessels. Since no tracer was ever identified among the parenchymal elements of the organ these data suggest that a blood-organ (blood-bursa) barrier may exist similar to that found in thymus and brain.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF00217582

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