ISSN:
1040-0397
Keywords:
Pyrroloquinoline quinone
;
Polyamines
;
Immobilization
;
Biosensor
;
Thiol
;
Chemistry
;
Polymer and Materials Science
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Pyrroloquinoline quinone (PQQ) was immobilized on gold electrodes by prior adsorption of the polyamines polyethylenimine, and triethylene tetraamine, followed by carbodiimide coupling of PQQ to the surface-adsorbed amine groups. The stability and electrochemical behavior of the electrodes, in which the amino-containing linker molecule is adsorbed on the electrode surface, were compared with those of electrodes prepared by carbodiimide coupling of PQQ to a cystamine monolayer, in which the sulfur-containing linker molecule is associated with the gold surface. The electrodes prepared using adsorbed polyethylenimine showed comparable stability to those based on a cystamine monolayer, but reveal enhanced stability to application of negative potentials (〈 -1.1 V). The method provides an alternative to the conventional functionalization of Au electrodes by thiols.
Additional Material:
4 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/elan.1140081203
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