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  • 1
    Electronic Resource
    Electronic Resource
    Stereoselective detection of amino acids by lobster olfactory receptor neurons (1993)
    Springer
    Journal of comparative physiology 171 (1993), S. 705-712 
    Details
    ISSN: 1432-1351
    Keywords: Olfaction ; Amino acid ; Receptor binding ; Electrophysiology ; Lobster
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary 1. Biochemical and electrophysiological assays were used to test the hypothesis that the olfactory system of the Caribbean spiny lobster, Panulirus argus, contains populations of chemosensory receptors that are differentially sensitive to the L- and D-stereoisomers of the amino acid alanine. 2. Independent binding sites for L-alanine (dissociation constant (K d ) of 6.6 μM and maximum binding (Bmax) of 16.8 fmole/μg protein) and for D-alanine (K d of 21.6 μM and Bmax of 17.8 fmole/μg protein) were characterized biochemically. The interaction of ligand with each binding site is rapid, reversible and saturable with respect to both time and concentration. 3. Based on a difference of at least 20% in the relative sensitivity of an olfactory receptor cell to alanine enantiomers, 44% and 34% of the 77 neurons tested were classified as L-alanine and D-alanine sensitive, respectively. The relative sensitivity to alanine enantiomers was independent of the concentration tested. Stereoselective receptors are likely for 17 of 20 other amino acids tested. 4. The congruence of biochemical and electrophysiological results leads to the conclusion that the lobster's responses to D- and L-alanine are mediated by receptors specific for each stereoisomer and that the receptors are differentially distributed among receptor cells.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00213067
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Specificity and sensitivity of the olfactory organ of the zebrafish, Danio rerio (1995)
    Springer
    Journal of comparative physiology 177 (1995), S. 191-199 
    Details
    ISSN: 1432-1351
    Keywords: Olfaction ; Amino acids ; Bile acids ; Zebrafish ; Electrophysiology
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract 1. The specificity and sensitivity of the olfactory organ of adult zebrafish, Danio rerio, to selected amino acid, bile acid, and steroid odorants were characterized using the electro-olfactogram recording technique. The olfactory organ was responsive to 28 of the 29 odorants tested. 2. All of the 100 μM amino acid and bile acid stimulants elicited a negative-going response that was significantly greater than the response to the artificial freshwater control. The general pattern of relative stimulatory effectiveness established for the amino acid stimuli was neutral amino acids 〉 basic amino acids 〉 acidic amino acids 〉 imino acids. The general pattern of relative stimulatory effectiveness of 100 μM bile acid stimuli was taurine-conjugated bile acids 〉 glycineconjugated bile acids ≈ non-conjugated bile acids. The responses to the most stimulatory bile acid odorants were up to 40% larger than the responses to the most stimulatory amino acid odorants. 3. The response threshold for cysteine and taurocholic acid, the most stimulatory of the amino acid and bile acid stimuli tested, was approximately 10-8 M. Females are significantly more sensitive to these odorants than males.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00225098
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  • 3
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    Neutron diffraction measurements and first-principles study of thermal motion of atoms in select M_{n+1}AX_{n} and binary MX transition-metal carbide phases (2012)
    American Physical Society (APS)
    Details
    Publication Date: 2012-12-04
    Description: Author(s): Nina J. Lane, Sven C. Vogel, Gilles Hug, Atsushi Togo, Laurent Chaput, Lars Hultman, and Michel W. Barsoum Herein, we compare the thermal vibrations of atoms in select ternary carbides with the formula M n +1 A X n (“ MAX phases,” M = Ti, Cr; A = Al, Si, Ge; X = C, N) as determined from first-principles phonon calculations to those obtained from high-temperature neutron powder diffraction studies. The transiti... [Phys. Rev. B 86, 214301] Published Mon Dec 03, 2012
    Keywords: Dynamics, dynamical systems, lattice effects
    Print ISSN: 1098-0121
    Electronic ISSN: 1095-3795
    Topics: Physics
    Published by American Physical Society (APS)
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