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  • 1
    Online Resource
    Online Resource
    Tumor Microenvironment : Molecular Players – Part B (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Cancer. ; Cytology. ; Internal medicine. ; Cancer Microenvironment. ; Cancer Biology. ; Cell Biology. ; Internal Medicine.
    Description / Table of Contents: MicroRNAs in the tumor microenvironment -- The Impact of Estrogen in the Tumor Microenvironment -- The non-bone related role of RANK/RANKL signaling in cancer -- Modulation of Cancer Cell Growth and Progression by Caveolin-1 in the Tumor Microenvironment -- Exosomes: Novel Players of Therapy Resistance in Neuroblastoma -- COX-2 Signaling in the Tumor Microenvironment -- Renin–angiotensin system in the tumor microenvironment -- Stem cell secreted factors in the tumor microenvironment -- Tight interplay between therapeutic monoclonal antibodies and the tumor microenvironment in cancer therapy -- Tumor Microenvironment & Nitric Oxide: Concepts and Mechanisms -- Index.
    Abstract: This book provides a comprehensive overview of the latest research on the molecular players in the tumor microenvironment, including MicroRNAs, estrogen, Caveolin-1, Nitric Oxide, RANK/RANKL signaling, , COX-2 Signaling, Renin–angiotensin system, and more. Taken alongside its companion volumes, Tumor Microenvironment: Molecular Players – Part B updates us on what we know about the tumor microenvironment, as well as future directions. This book is essential reading for advanced cell biology and cancer biology students as well as researchers seeking an update on research in the tumor microenvironment.
    Type of Medium: Online Resource
    Pages: XIV, 162 p. 22 illus., 21 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030502249
    Series Statement: Advances in Experimental Medicine and Biology, 1277
    URL: https://doi.org/10.1007/978-3-030-50224-9
    DOI: 10.1007/978-3-030-50224-9
    DDC: 571.978
    Language: English
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  • 2
    Online Resource
    Online Resource
    Tumor Microenvironment : Signaling Pathways – Part B (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Cancer. ; Biophysics. ; Cell interaction. ; Cytology. ; Cancer Microenvironment. ; Mechanobiological Cell Signaling. ; Cell Biology. ; Cancer Biology.
    Description / Table of Contents: Neuregulin signaling in the tumor microenvironment -- HGF/c-Met signalling in the tumor microenvironment -- Eph/ephrin signaling in the tumor microenvironment -- Src signaling in cancer and tumor microenvironment -- Purinergic signaling within the tumor microenvironment -- TGFβ signalling in the tumor microenvironment -- Wnt Signaling in the Tumor Microenvironment -- Lysophospholipid Signalling and the Tumour Microenvironment -- Adenosine signaling in the tumor microenvironment -- Androgen signaling in the tumor microenvironment -- Index.
    Abstract: Revealing essential roles of the tumor microenvironment in cancer progression, this book provides a comprehensive overview of the latest research on how different signaling pathways are important in the tumor microenvironment. Multiple signaling pathways are covered, including Src, Neuregulin, Adenosine, TGFβ, Androgen, Wnt, and more. Taken alongside its companion volumes, these books update us on what we know about various aspects of the tumor microenvironment as well as future directions. Tumor Microenvironment: Signaling Pathways – Part B is essential reading for advanced cell biology and cancer biology students as well as researchers seeking an update on research in the tumor microenvironment.
    Type of Medium: Online Resource
    Pages: XIII, 191 p. 31 illus., 25 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030471897
    Series Statement: Advances in Experimental Medicine and Biology, 1270
    URL: https://doi.org/10.1007/978-3-030-47189-7
    DOI: 10.1007/978-3-030-47189-7
    DDC: 571.978
    Language: English
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  • 3
    Online Resource
    Online Resource
    Tumor Microenvironment : Signaling Pathways – Part A (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Cytology. ; Cancer. ; Oncology. ; Cell Biology. ; Cancer Biology. ; Oncology.
    Description / Table of Contents: Shaping of the tumor microenvironment by Notch signaling -- Erythropoietin signaling in the microenvironment of tumors and healthy tissues -- Neuropilin – handyman and power broker in the tumor microenvironment -- Translational landscape of mTOR signaling in integrating cues between cancer and tumor microenvironment -- Toll-like receptors signaling in the tumor microenvironment -- Rho-ROCK signaling in normal physiology and as a key player in shaping the tumor microenvironment -- S1P signaling in the tumor microenvironment -- CD200-CD200R pathway in the regulation of tumor immune microenvironment and immunotherapy -- Index.
    Abstract: Revealing essential roles of the tumor microenvironment in cancer progression, this book provides a comprehensive overview of the latest research on how different signaling pathways are important in the tumor microenvironment. Multiple signaling pathways are covered, including S1P, neuregulin, Notch, erythropoietin, Rho-ROCK, mTOR, and more. Taken alongside its companion volumes, these books update us on what we know about various aspects of the tumor microenvironment as well as future directions. Tumor Microenvironment: Signaling Pathways – Part A is essential reading for advanced cell biology and cancer biology students as well as researchers seeking an update on research in the tumor microenvironment.
    Type of Medium: Online Resource
    Pages: XI, 170 p. 38 illus., 35 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030355821
    Series Statement: Advances in Experimental Medicine and Biology, 1223
    URL: https://doi.org/10.1007/978-3-030-35582-1
    DOI: 10.1007/978-3-030-35582-1
    DDC: 571.6
    Language: English
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  • 4
    Online Resource
    Online Resource
    Tumor Microenvironment : Hematopoietic Cells – Part A (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Cytology. ; Cancer. ; Oncology. ; Cell Biology. ; Cancer Biology. ; Oncology.
    Description / Table of Contents: Neutrophils in the Tumor Microenvironment -- Basophils in Tumor Microenvironment and Surroundings -- Janus or Hydra: The many faces of T helper cells in the human tumour microenvironment -- Cytotoxic CD8+ lymphocytes in the tumor microenvironment -- Mucosal-associated invariant T cells in tumors of epithelial origin -- Fibrocytes in the Tumor Microenvironment -- Models for Monocytic Cells in the Tumor Microenvironment -- Myeloid-Derived Suppressor Cells in the Tumor Microenvironment -- Index.
    Abstract: Revealing essential roles of the tumor microenvironment in cancer progression, this book focuses on the role of hematopoietic components of the tumor microenvironment. Further, it teaches readers about the roles of distinct constituents of the tumor microenvironment and how they affect cancer development. Topics include neutrophils, basophils, T helper cells, cytotoxic lymphocytes, fibrocytes, and myeloid-derived suppressor cells, and more. Taken alongside its companion volumes, these books update us on what we know about various aspects of the tumor microenvironment as well as future directions. Tumor Microenvironment: Hematopoietic Cells – Part A is essential reading for advanced cell biology and cancer biology students as well as researchers seeking an update on research in the tumor microenvironment.
    Type of Medium: Online Resource
    Pages: XI, 146 p. 19 illus., 17 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030357238
    Series Statement: Advances in Experimental Medicine and Biology, 1224
    URL: https://doi.org/10.1007/978-3-030-35723-8
    DOI: 10.1007/978-3-030-35723-8
    DDC: 571.6
    Language: English
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  • 5
    Online Resource
    Online Resource
    Tumor Microenvironment : Extracellular Matrix Components – Part B (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Cancer. ; Stem cells. ; Regenerative medicine. ; Cytology. ; Cancer Microenvironment. ; Cancer Biology. ; Stem Cell Biology. ; Regenerative Medicine and Tissue Engineering. ; Cell Biology.
    Description / Table of Contents: Elastin in the Tumor Microenvironment -- Decorin in the tumor microenvironment -- Syndecan-1 in the tumor microenvironment -- Versican in the tumor microenvironment -- Chondroitin Sulphate Proteoglycans in the Tumour Microenvironment -- Lipoproteins and the Tumor Microenvironment -- The Role of BEHAB/Brevican in the Tumor Microenvironment: Mediating Glioma Cell Invasion and Motility -- Thrombospondin in Tumor Microenvironment -- Tenascin-C function in glioma: immunomodulation and beyond -- Index.
    Abstract: Revealing essential roles of the tumor microenvironment in cancer progression, this volume focuses on the extracellular matrix components of the tumor microenvironment during cancer development. Furthermore, it teaches readers about the roles of distinct constituents of the tumor microenvironment and how they affect cancer development. Topics include elastin, decorin, syndecan-1, versican, lipoproteins, brevican, thrombospondin, and much more. Taken alongside its companion volumes, Tumor Microenvironment: Extracellular Matrix Components – Part B updates us on what we know about the different aspects of the tumor microenvironment, as well as apprises us on the future advances in the field. For the newest generation of researchers, this volume serves as a useful introduction to the history of scientists’ focus on the tumor microenvironment, and explores how this knowledge is currently applied in cancer treatments. The book is an essential text for advanced cell biology and cancer biology students, as well as for scientists seeking an update on the developments in tumor microenvironment research. All of the chapters authors are renowned international experts in the field of cancer biology, and in the specific subfields that are the focus of their chapters.
    Type of Medium: Online Resource
    Pages: XIII, 178 p. 36 illus., 33 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030484576
    Series Statement: Advances in Experimental Medicine and Biology, 1272
    URL: https://doi.org/10.1007/978-3-030-48457-6
    DOI: 10.1007/978-3-030-48457-6
    DDC: 571.978
    Language: English
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  • 6
    Online Resource
    Online Resource
    Tumor Microenvironment : Molecular Players – Part A (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Cytology. ; Cancer. ; Oncology. ; Cell Biology. ; Cancer Biology. ; Oncology.
    Description / Table of Contents: Cathepsin D in the tumor microenvironment of breast and ovarian cancers -- Galectins in the tumor microenvironment: Focus on galectin-1 -- Iron in the tumor microenvironment -- Oxygen in the tumor microenvironment: mathematical and numerical modeling -- Roles for Phospholipase D1 in the tumor microenvironment -- Leptin in tumor microenvironment -- The immune consequences of lactate in the tumor microenvironment -- Fatty acid mediators in the tumor microenvironment -- Extracellular Vesicles in the tumor microenvironment: various implications in tumor progression -- Index.
    Abstract: This book provides a comprehensive overview of the latest research on the molecular players in the tumor microenvironment, including Cathepsin D, galectins, iron, oxygen, Phospholipase D1, leptin, extracellular vesicles, and more. Taken alongside its companion volumes, these books update us on what we know about the tumor microenvironment as well as future directions. Tumor Microenvironment: Molecular Players – Part A is essential reading for advanced cell biology and cancer biology students as well as researchers seeking an update on research in the tumor microenvironment.
    Type of Medium: Online Resource
    Pages: XII, 175 p. 31 illus., 20 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030430931
    Series Statement: Advances in Experimental Medicine and Biology, 1259
    URL: https://doi.org/10.1007/978-3-030-43093-1
    DOI: 10.1007/978-3-030-43093-1
    DDC: 571.6
    Language: English
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  • 7
    Online Resource
    Online Resource
    Tumor Microenvironments in Organs : From the Brain to the Skin – Part A (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Cytology. ; Cancer. ; Oncology. ; Cell Biology. ; Cancer Biology. ; Oncology.
    Description / Table of Contents: The intestinal tumour microenvironment -- Gastric Tumor Microenvironment -- Parathyroid tumor microenvironment -- Microenvironment in Cardiac Tumor Development: What Lies Beyond the Event Horizon? -- The roles of bone marrow-resident cells as a microenvironment for bone metastasis -- Adipose tumor microenvironment -- Appendix Tumor Microenvironment -- Spinal cord tumor microenvironment -- Cancer stem cell niche and immune-active tumor microenvironment in testicular germ cell tumors -- Tumor microenvironment in skin carcinogenesis -- Index.
    Abstract: Revealing essential roles of the tumor microenvironment in cancer progression, this book provides a comprehensive overview of the latest research on the tumor microenvironment in over thirty human organs, including the parathyroid gland, heart, intestine, testicles, and more. Taken alongside its companion volumes, these books update us on what we know about the different aspects of the tumor microenvironments in distinct organs as well as future directions. Tumor Microenvironments in Organs: From the Brain to the Skin – Part A is essential reading for advanced cell biology and cancer biology students as well as researchers seeking an update on research in the tumor microenvironment.
    Type of Medium: Online Resource
    Pages: XII, 147 p. 25 illus., 24 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030362140
    Series Statement: Advances in Experimental Medicine and Biology, 1226
    URL: https://doi.org/10.1007/978-3-030-36214-0
    DOI: 10.1007/978-3-030-36214-0
    DDC: 571.6
    Language: English
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  • 8
    Online Resource
    Online Resource
    Tumor Microenvironment : The Role of Interleukins – Part A (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Cytology. ; Cancer. ; Oncology. ; Cell Biology. ; Cancer Biology. ; Oncology.
    Description / Table of Contents: IL-1 signaling in tumor microenvironment -- Interleukin-8 in the Tumor Immune Niche: Lessons from Comparative Oncology -- IL-9 and Th9 cells in tumor immunity -- IL-17 signaling in the tumor microenvironment -- Emerging roles for Interleukin-18 in the gastrointestinal tumor microenvironment -- IL-21 signaling in the tumor microenvironment -- ST2 signaling in the tumor microenvironment -- IL-36 Signaling in the Tumor Microenvironment -- Index.
    Abstract: Revealing essential roles of the tumor microenvironment in cancer progression, this book provides a comprehensive overview of the latest research on the role of interleukins in the tumor microenvironment. Each chapter focuses on the various ways to target the tumor microenvironment by intervention in the interleukin biology, including IL-1, IL-8, IL-21, IL-36 signaling, and more. Taken alongside its companion volumes, Tumor Microenvironment: The Role of Interleukins – Part A updates us on what we know about various aspects of the tumor microenvironment, as well as future directions. This book is essential reading for advanced cell biology and cancer biology students as well as researchers seeking an update on research in the tumor microenvironment.
    Type of Medium: Online Resource
    Pages: X, 115 p. 23 illus., 22 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030383152
    Series Statement: Advances in Experimental Medicine and Biology, 1240
    URL: https://doi.org/10.1007/978-3-030-38315-2
    DOI: 10.1007/978-3-030-38315-2
    DDC: 571.6
    Language: English
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  • 9
    Online Resource
    Online Resource
    Tumor Microenvironment : Hematopoietic Cells – Part B (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Cancer. ; Hematopoietic system. ; Cytology. ; Cancer Microenvironment. ; Haematopoietic System. ; Cell Biology. ; Cancer Biology.
    Description / Table of Contents: Eosinophils in the tumor microenvironment -- Dendritic cells in the tumor microenvironment -- Resident memory T cells in the tumor microenvironment -- NK cells in the tumor microenvironment -- γδ T cells in tumor microenvironment -- Regulatory T Cells in the Tumor Microenvironment -- The Hematopoietic Microenvironment in Myeloproliferative Neoplasms: The Interplay Between Nature (Stem Cells) and Nurture (the Niche) -- Langerhans cells in the tumor microenvironment -- Mast cells in the tumor microenvironment -- B cells in the gastrointestinal tumor microenvironment with a focus on pancreatic cancer: opportunities for precision medicine? -- Microglia in the Brain Tumor Microenvironment -- Index.
    Abstract: Revealing essential roles of the tumor microenvironment in cancer progression, this book focuses on the role of hematopoietic components of the tumor microenvironment. Further, it teaches readers about the roles of distinct constituents of the tumor microenvironment and how they affect cancer development. Topics include eosinophils, NK cells, γδ T cells, regulatory T Cells, Langerhans cells, hematopoietic stem cells, Mast cells, B cells and Microglia, and more. Taken alongside its companion volumes, Tumor Microenvironment: Hematopoietic Cells – Part B updates us on what we know about various aspects of the tumor microenvironment as well as future directions. This book is essential reading for advanced cell biology and cancer biology students as well as researchers seeking an update on research in the tumor microenvironment.
    Type of Medium: Online Resource
    Pages: XIV, 215 p. 26 illus., 24 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030492700
    Series Statement: Advances in Experimental Medicine and Biology, 1273
    URL: https://doi.org/10.1007/978-3-030-49270-0
    DOI: 10.1007/978-3-030-49270-0
    DDC: 571.978
    Language: English
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  • 10
    Online Resource
    Online Resource
    Tumor Microenvironment : Novel Concepts (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Cancer. ; Cytology. ; Cancer Microenvironment. ; Cell Biology. ; Cancer Biology.
    Description / Table of Contents: 1. The Tumour Microenvironment and Circulating Tumour Cells: A partnership driving metastasis and glycan-based opportunities for cancer control -- 2. Dormancy in the Tumor Microenvironment -- 3. Tumor-associated tertiary lymphoid structures: A cancer biomarker and a target for next-generation immunotherapy -- 4. Studying the tumor microenvironment in zebrafish -- 5. Pre-metastatic niche formation by neutrophils in different organs -- 6. Tumor cell invasion and the tumor microenvironment: Special focus on brain tumors -- 7. The dog as a model to study the tumor microenvironment -- 8. EFFEROCYTOSIS AND THE STORY OF “FIND ME’’, ‘’EAT ME” AND “DON’T EAT ME” SIGNALING IN THE TUMOR MICRO ENVIRONMENT -- 9. Color-coded imaging of the tumor micro-environment (TME) in human patient-derived orthotopic xenograft (PDOX) mouse models -- 10. Mitochondria and the tumor microenvironment in blood cancer -- 11. Telocytes in the tumor microenvironment -- 12. Modeling the roles of astrocytes in the metastatic tumor cell microenvironment -- 13. Roles of fibroblasts in microenvironment formation associated with radiation-induced cancer -- 14. Tumor microenvironment-associated pericyte populations may impact therapeutic response in thyroid cancer -- 15. The adrenergic nerve network in cancer -- 16. Current treatment modalities targeting tumor microenvironment in castration-resistant prostate cancer -- 17.Brain metastases and tumor microenvironment -- 18. MIGRATION STIMULATING FACTOR (MSF). ITS ROLE IN THE TUMOUR -- MICROENVIRONMENT -- 19. Mechanical Signaling in the Mammary Microenvironment - from Homeostasis to Cancer -- 20. Osteopontin Signaling in Shaping Tumor Microenvironment Conducive to Malignant Progression -- 21. Progesterone receptor signaling in the breast tumor microenvironment -- 22. Progranulin/GP88, a complex and multi-faceted player of tumor growth by direct action and via the tumor microenvironmen -- 23. Sex-based differences in the tumor microenvironmet. .
    Abstract: This volume discusses novel concepts in cancer biology, focusing on different factors that affect the tumor microenvironment. Topics covered include sex-based differences in the tumor microenironment, dormancy in the tumor microenvironment, the influence of obesity on the tumor microenvironment, and much more. Taken alongside its companion volumes, Tumor Microenvironment: Novel Concepts covers the latest research on various aspects of the tumor microenvironment, as well as future directions. Useful for introducing the newer generation of researchers to the history of how scientists studied the tumor microenvironment as well as how this knowledge is currently applied for cancer treatments, it will be essential reading for advanced cell biology and cancer biology students, as well as researchers seeking an update on research on the tumor microenvironment.
    Type of Medium: Online Resource
    Pages: XIII, 548 p. 79 illus., 72 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030731199
    Series Statement: Advances in Experimental Medicine and Biology, 1329
    URL: https://doi.org/10.1007/978-3-030-73119-9
    DOI: 10.1007/978-3-030-73119-9
    DDC: 571.978
    Language: English
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