ISSN:
0170-2041
Keywords:
Pyridine derivatives, 2-thioxo-
;
Thioacetanilides
;
Cinnamates, α-cyano-
;
Malononitriles, arylmethylene-
;
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
The synthesis of substituted 2-thioxopyridines from benzoyl(thioacetanilides) 1 and arylmethylenemalononitriles or ethyl α-cyanocinnamates 2 is described. The reaction of 1 with 2b, c gives rise to derivatives of tetrahydro- 5 and dihydro-6-thioxopyridines 6. A 4,5-cis configuration of 5 is proposed on the basis of the analysis of the vicinal coupling constants.
Additional Material:
1 Tab.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/jlac.1990199001209
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