ISSN:
1432-1017
Keywords:
Ribonuclease T1 (Aspergillus oryzae)
;
Ribonuclease Ms (Aspergillus saitoi)
;
Ribonuclease Pchl (Penicillium chrysogenum)
;
Structure prediction
;
Computer graphics
;
Energy minimization
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Physics
Notes:
Abstract In this paper we predict the structure of RNase Pch1 as modelled from the previously predicted structure of RNase Ms and the crystal structure of RNase T1 in the complex with 2′GMP. The predicted structures and their initial energy minimized structural RNase T1 template are compared. The predicted structures of RNase Pch1 show, independent of their prediction form RNase Ms or T1, a higher structural similarity to RNase T1 than to RNase Ms, in agreement with higher sequence similarity and specificity — RNaes T1 and Pchl are specific for guanine whereas RNase Ms is base-unspecific with preference for guanine.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00183375
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