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  • Column liquid chromatoraphy  (1)
  • non-specific resistance  (1)
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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    European journal of clinical pharmacology 7 (1974), S. 415-419 
    ISSN: 1432-1041
    Keywords: Impulsin ; non-specific resistance ; acute respiratory tract infections ; man
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary Two large scale, double-blind field trials were conducted to test the efficacy of Impulsin (N-2-hydroxyethyl palmitamide) in reducing the incidence and severity of respiratory tract infections. The results suggested that repeated daily intake of Impulsin 30 mg per kg helped to prevent virus infections of the respiratory tract, since it produced a statistically significant reduction in the incidence of illness. Prophylactic treatment with Impulsin markedly diminished the number of episodes of fever, headache and sore throat, whilst catarrhal symptoms were much less affected. The administration of Impulsin had no effect on the mean duration of disability and fever, which suggests that the severity of the diseases was not affected.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Chromatographia 26 (1988), S. 206-208 
    ISSN: 1612-1112
    Keywords: Column liquid chromatoraphy ; Metipamide ; Blood pressure reduction ; Clinical trials
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Summary Metipamide was monitored during a two month cap period of treatment to determine whether the wholeblood levels estimated by HPLC provide a relevant indicator of the possible accumulation of the drug., We also analysed antihypertensive activity and biochemical changes in blood of twenty hypertonic patients. Result showed that metipamide is an effective, first-line antihypertensive agent, combining statisfactory blood pressure reduction with low frequency of side effects and a simple once-daily dosage regime.
    Type of Medium: Electronic Resource
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