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  • 1
    ISSN: 1573-0832
    Keywords: Amphotericin B ; Aspergillus spp. ; Clotrimazole ; In vitro susceptibility ; Itraconazole
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract The susceptibilities of two isolates ofAspergillus flavus, one from a human case of recalcitrant mycotic keratitis, and an environmental isolate ofA. fumigatus, to itraconazole, clotrimazole and amphotericin B were measured. Observations of macroscopic growth and microscopic evaluations of conidia germination both indicated that the two isolates ofA. flavus were markedly more resistant to amphotericin B than to itraconazole and clotrimazole. Itraconazole was more effective than clotrimazole for all isolates. Ourin vitro susceptibility results suggest the use of itraconazole should be a primary consideration in the treatment ofAspergillus keratitis.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1573-0832
    Keywords: Aspergillus fumigatus ; Aspergillus versicolor ; Fiberglass extracts ; Formaldehyde ; Urea
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Water extracts of thermal and acoustic fiberglass insulations used in the duct work of heating, ventilation and air conditioning (HVAC) systems supported germination of conidia and growth ofAspergillus versicolor (Vuillemin) Tiraboschi 1908–9 andAspergillus fumigatus Fresenius 1863. Urea, formaldehyde and unidentified organics were detected in the extracts. Formaldehyde in concentrations similar to those found in the extracts restricted the growth of both species in enriched media.A. versicolor, the more common species associated with fiberglass insulations, was more resistant to formaldehyde thanA. fumigatus.
    Type of Medium: Electronic Resource
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