Publication Date:
2001-12-18
Description:
The 5.67-megabase genome of the plant pathogen Agrobacterium tumefaciens C58 consists of a circular chromosome, a linear chromosome, and two plasmids. Extensive orthology and nucleotide colinearity between the genomes of A. tumefaciens and the plant symbiont Sinorhizobium meliloti suggest a recent evolutionary divergence. Their similarities include metabolic, transport, and regulatory systems that promote survival in the highly competitive rhizosphere; differences are apparent in their genome structure and virulence gene complement. Availability of the A. tumefaciens sequence will facilitate investigations into the molecular basis of pathogenesis and the evolutionary divergence of pathogenic and symbiotic lifestyles.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Wood, D W -- Setubal, J C -- Kaul, R -- Monks, D E -- Kitajima, J P -- Okura, V K -- Zhou, Y -- Chen, L -- Wood, G E -- Almeida, N F Jr -- Woo, L -- Chen, Y -- Paulsen, I T -- Eisen, J A -- Karp, P D -- Bovee, D Sr -- Chapman, P -- Clendenning, J -- Deatherage, G -- Gillet, W -- Grant, C -- Kutyavin, T -- Levy, R -- Li, M J -- McClelland, E -- Palmieri, A -- Raymond, C -- Rouse, G -- Saenphimmachak, C -- Wu, Z -- Romero, P -- Gordon, D -- Zhang, S -- Yoo, H -- Tao, Y -- Biddle, P -- Jung, M -- Krespan, W -- Perry, M -- Gordon-Kamm, B -- Liao, L -- Kim, S -- Hendrick, C -- Zhao, Z Y -- Dolan, M -- Chumley, F -- Tingey, S V -- Tomb, J F -- Gordon, M P -- Olson, M V -- Nester, E W -- GM19642/GM/NIGMS NIH HHS/ -- GM32618/GM/NIGMS NIH HHS/ -- New York, N.Y. -- Science. 2001 Dec 14;294(5550):2317-23.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Microbiology, University of Washington, 1959 NE Pacific Street, Box 357242, Seattle, WA 98195, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/11743193" target="_blank"〉PubMed〈/a〉
Keywords:
Agrobacterium tumefaciens/classification/*genetics/pathogenicity/physiology
;
Bacterial Adhesion/genetics
;
Bacterial Proteins/genetics/metabolism
;
Carrier Proteins/genetics/metabolism
;
Chromosomes, Bacterial/genetics
;
Conjugation, Genetic
;
DNA Replication
;
Genes, Bacterial
;
Genes, Regulator
;
*Genome, Bacterial
;
Membrane Proteins/genetics/metabolism
;
Molecular Sequence Data
;
Phylogeny
;
Plants/microbiology
;
Plasmids
;
Replicon
;
Rhizobiaceae/genetics/physiology
;
*Sequence Analysis, DNA
;
Sinorhizobium meliloti/genetics/physiology
;
Symbiosis
;
Virulence/genetics
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
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