ISSN:
1432-072X
Keywords:
Chlamydomonas
;
Acetamidase
;
Gene Regulation
;
Fluoro-acetamide toxicity
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
Notes:
Abstract Chlamydomonas reinhardi can utilise the lower aliphatic amides (C1−C4) as nitrogen sources. Of these only acetamide can serve as a sole carbon source. The acetamide analogue F-acetamide kills cells after conversion to F-acetate and F-citrate. This conversion is controlled by exogenous ammonia and, in part, acetate levels. Only one enzyme and one active site are involved in acetamidase function. Enzymatic analysis indicates an increased substrate range as compared to the growth — supported range, indicating uptake, toxicity or metabolic control restrictions.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00422535
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