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  • Chemistry  (9)
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  • 1
    Electronic Resource
    Electronic Resource
    Gel-fabric prostheses of the ureter (1967)
    Hoboken, NJ : Wiley-Blackwell
    Journal of Biomedical Materials Research 1 (1967), S. 325-336 
    Details
    ISSN: 0021-9304
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine , Technology
    Notes: In 14 canines the ureter was substituted with a new type of ureteral gel-fabric prosthesis. The prosthesis is a tube of knitted fabric of polyester fiber case in a layer of hydrophilous glycol methacrylate gel. Anastomoses were carried out by inserting the prosthesis ends into the ureter lumen and by suturing the stump of the ureter to a special fixing ring on the prosthesis. Preliminary results of short-term obsevations (4 months) are quite promising. The prosthesis is non-irritating and conducts the urine satisfactorily.
    Additional Material: 9 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jbm.820010304
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  • 2
    Electronic Resource
    Electronic Resource
    Use of spongy hydron in plastic surgery (1968)
    Hoboken, NJ : Wiley-Blackwell
    Journal of Biomedical Materials Research 2 (1968), S. 237-243 
    Details
    ISSN: 0021-9304
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine , Technology
    Notes: A hydrophilic plastic material (USA trademark Hydron), developed by Wichterle and Lím, was used as a sponge for augmentation of breasts in the clinic for plastic surgery. The preparation of the prosthesis and the operational procedures are described.
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jbm.820020207
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  • 3
    Electronic Resource
    Electronic Resource
    Water sorption and mechanical properties of 2-hydroxyethyl-methacrylate and methylmethacrylate copolymers (1984)
    Hoboken, NJ : Wiley-Blackwell
    Journal of Biomedical Materials Research 18 (1984), S. 137-146 
    Details
    ISSN: 0021-9304
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine , Technology
    Notes: Randomly cross-linked copolymers of 2-hydroxyethyl-methacrylate (HEMA) and methyl-methacrylate (MMA) have been prepared and studied in the dry and swollen state. Tensile and indentation tests indicate that by changing the composition of copolymers, it is possible to obtain materials with a wide range of mechanical properties and corresponding glass transition temperatures. Water diffusion coefficients in sorption and desorption experiments have been calculated and compared.
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jbm.820180204
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  • 4
    Electronic Resource
    Electronic Resource
    Employment of hydron polymer antibiotic vehicle in otolaryngology (1969)
    Hoboken, NJ : Wiley-Blackwell
    Journal of Biomedical Materials Research 3 (1969), S. 443-454 
    Details
    ISSN: 0021-9304
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine , Technology
    Notes: Hydrophilic poly (glycolmethacrylate) HydronU. S. Trade Mark, National Patent Development Corporation, 375 Park Avenue, New York, N. Y. gels were used as vehicles for selected antibiotics. Polymer vehicles with various antibiotics were prepared and their biological activity tested by sensitivity tests on solid and liquid media by means of reference microbe strains. Polymer vehicles with chosen antibiotics were implanted in rats and the rate of diffusion tested in vivo by removing the vehicles at fixed time intervals and ascertaining the content of the remaining antibiotic in the vehicle. In the clinical part, the favorable results of application of antibiotics saturated gel vehicles in tympanoplastic operations and healing of inflammatory states after middle-ear operations are described.
    Additional Material: 9 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jbm.820030306
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  • 5
    Electronic Resource
    Electronic Resource
    Equilibrium adsorption of human serum albumin and human fibrinogen on hydrophobic and hydrophilic surfaces (1984)
    Hoboken, NJ : Wiley-Blackwell
    Journal of Biomedical Materials Research 18 (1984), S. 685-693 
    Details
    ISSN: 0021-9304
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine , Technology
    Notes: The adsorption of human serum albumin and human fibrinogen on flat surfaces was quantitatively determined by measuring the decrease in UV absorption in the adsorption solution. The applicability of the method is discussed for hydrophilic and hydrophobic materials. The values of equilibrium adsorption are presented - albumin on polyethylene, and fibrinogen on polyethylene, carbon, poly(2-hydroxyethyl methacrylate), and cellophane.
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jbm.820180609
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  • 6
    Electronic Resource
    Electronic Resource
    Surgical suture materials coated with a layer of hydrophilic HydronU.S. Trademark, National Patent Development Corporation, 375 Park Avenue, New York, N. Y. gel (1969)
    Hoboken, NJ : Wiley-Blackwell
    Journal of Biomedical Materials Research 3 (1969), S. 305-313 
    Details
    ISSN: 0021-9304
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine , Technology
    Notes: Surgical suture materials were coated with a layer of hydrophilic Hydron gel. By tests carried out on tissue cultures, it has been verified that this layer itself improves the tolerance of the fiber by the organism. In addition, appropriate biologically active substances (e.g., antibiotics), preventing either the development or spreading of an infection along the fiber, may be incorporated into the gel layer. Neither the knotting ability nor other mechanical properties of the fiber are influenced by the gel coating. Preliminary clinical experiments showed good results.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jbm.820030210
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  • 7
    Electronic Resource
    Electronic Resource
    Study on a new soft denture liner of the sofdent type (1968)
    Hoboken, NJ : Wiley-Blackwell
    Journal of Biomedical Materials Research 2 (1968), S. 473-487 
    Details
    ISSN: 0021-9304
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine , Technology
    Notes: It has been shown that the admixture of diacetins in the capacity of a diluent in the polymerization of hydrophilic poly(ethyleneglycol methacrylate) gels improves the properties of products used as soft denture liners, especially by inhibiting the volume changes caused by swelling, and by improving the mechanical properties of gels as well as the strength of bond between the gel and the basic material of the prosthesis.
    Additional Material: 9 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jbm.820020408
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  • 8
    Electronic Resource
    Electronic Resource
    Mechanical properties of model synthetic tendonsPartly presented at the 8th International Congress on Rheology, Naples, September 1980. (1981)
    Hoboken, NJ : Wiley-Blackwell
    Journal of Biomedical Materials Research 15 (1981), S. 147-157 
    Details
    ISSN: 0021-9304
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine , Technology
    Notes: Model synthetic tendons consisting of 20 vol % of texturized poly(ethylene terephthalate) fibers and of the water-swollen poly(2-hydroxyethyl methacrylate) matrix have the tensile modulus E = 1.5 ± 0.1 GPa, strength and strain-at-break σb = 85 ± 10 MPa and ∊b = 0.08 ± 0.02. The force required for breaking tendons with the diameters 2, 3, 4 mm is, respectively, 300, 500, and 960 N. By these properties model synthetic tendons closely imitate the properties of natural tendons. Long-term (100 min) and repeated short-term (30 times 1 min) creep shows that on loading model tendons lose some 10% of their stiffness, but that the whole deformation is reversible. The shape of the compliance vs. time dependence of synthetic tendons closely resembles the dependence determined for the parent fiber. The stiffness and strength of a tendon are given by those of the fiber bundle used; by varying fiber volume fraction, it is possible to adjust the required mechanical properties of tendons.
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jbm.820150204
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  • 9
    Electronic Resource
    Electronic Resource
    The removal of residuals and oligomers from poly(2-hydroxyethylmethacrylate) (1985)
    Hoboken, NJ : Wiley-Blackwell
    Journal of Biomedical Materials Research 19 (1985), S. 1169-1179 
    Details
    ISSN: 0021-9304
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine , Technology
    Notes: Poly(2-hydroxyethyl methacrylate) gels obtained by the cross-linking polymerization using four different free-radical initiators were washed with water. Chromatographically, the eluate appeared to be a mixture of low-molecular-weight compounds and of a small amount of the high-molecular-weight component. The UV and IR absorption spectra of compounds present in the eluate were compared with those of model compounds that were assumed to exist in the gel as impurities after the polymerization (monomers and oligomers of hydroxyethyl methacrylate, decomposition products of initiators). Time dependences of the removal of impurities from the gels by washing were measured. Most of the impurities were washed out within a few hours. In addition to the assumed impurities, the eluate was found to contain an unidentified compound that was still washed out after several months. Intracutaneous applications of this compound did not produce local irritation of the tested tissue.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jbm.820190923
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