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  • 1
    ISSN: 1045-4861
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine , Technology
    Notes: Two new cardiovascular monofilament sutures attached to taper point needles have been developed for use in expanded polytetrafluoroethylene (PTFE) grafts. One monofilament suture made of PTFE has a microporous structure that allows it to be channel swaged to a needle that closely approximates its suture diameter. The other suture is a monofilament polypropylene suture that has been extruded to produce a tapered swage end, which was significantly smaller than that of the remainder of the suture in order to be channel swaged to smaller diameter needles. On the basis of comprehensive biomechanical performances, the performance of the new needle suture products with needle/suture diameter ratios approaching 1:1 was superior to needle suture products with 2:1 needle/suture diameter ratios for use in PTFE vascular grafts, regardless of the suture material. © 1993 John Wiley & Sons, Inc.
    Additional Material: 8 Ill.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Applied Biomaterials 4 (1993), S. 157-160 
    ISSN: 1045-4861
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine , Technology
    Notes: Needle performance is primarily judged by its penetration through tissue. For detailed studies of needle performance, tissue is too heterogeneous and unstable and difficult to obtain. A homogeneous, stable, and readily available polyurethane substrate has been evaluated as a suitable alternative to biological tissue for evaluation of needle penetration. The needle penetration profiles through the synthetic substrate correlated very well with those through natural tissue. In addition, the synthetic substrate was sensitive enough to easily detect a 20% increase in the force necessary to penetrate natural tissue. This polyurethane substrate offers a valid alternative to biological tissue for the testing of needle penetration performance. © 1993 John Wiley & Sons, Inc.
    Additional Material: 6 Ill.
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  • 3
    Electronic Resource
    Electronic Resource
    Stamford, Conn. [u.a.] : Wiley-Blackwell
    Polymer Engineering and Science 35 (1995), S. 1117-1123 
    ISSN: 0032-3888
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Double yields, as well as other complex yielding behavior, that are observed during the tensile deformation of the polyethylenes have been studied in a systematic manner. The conditions under which such yielding is observed were established by studying a set of linear polyethylenes and well-characterized ethylene copolymers of narrow molecular weight and composition distributions. A wide range in crystallinity levels were developed and the rate of deformation and the deformation temperature were varied. These experimental results make clear why such complex yielding processes are not always observed. A qualitative explanation, based on the postulate of a partial melting-recrystallization process during deformation, is given that encompasses all of the experimental data.
    Additional Material: 6 Ill.
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  • 4
    ISSN: 0173-0835
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Due to the nature of lipopolysaccharide endotoxin structures of bacterial pyrogens, their removal from solutions containing therapeutic proteins is often a problem in the pharmaceutical industry. In this report we describe the application of electromotive force to dislodge lipopolysaccharide endotoxins from proteins. This was performed by employing a multicompartment electrolyzer fitted with Immobiline membranes of specified pIs. A thousand-fold reduction of endotoxin could be achieved in the model test system described. This contribution describes the use of a new recycling isoelectric focusing approach without the use of carrier ampholytes.
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
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