ISSN:
0887-624X
Keywords:
radical polymerization
;
methacrylamide
;
(L)-leucine
;
N-methyl-(L)-leucine
;
Chemistry
;
Polymer and Materials Science
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Syntheses and radical polymerizations of methacrylamides having (L)-leucine and N-methyl-(L)-leucine methyl ester structures in the side chains N-methacryloyl-(L)-leucine methyl ester (MA-L-M) and N-methyl-N-methacryloyl-(L)-leucine methyl ester (N-Me-MA-L-M) were carried out. The monomers were prepared by the reactions of methacryloyl chloride with the corresponding amino acid methyl esters. Radical polymerizations were carried out in the presence of appropriate initiators at 60°C and 120°C. MA-L-M afforded the corresponding polymer with Mns 38,000 ∼ 372,000 in high yields, while N-Me-MA-L-M afforded a trace amount of polymer at 60°C and in a low yield even at 120°C. Both inversion and increase of absolute value of specific rotation were observed in the transformation from MA-L-M (+1.3°C) to poly(MA-L-M) (-35.7°C). Changes in the CD spectral pattern and the conformation of the leucine moiety were confirmed from the monomer to polymer. © 1998 John Wiley & Sons, Inc. J Polym Sci A: Polym Chem 36: 2681-2690, 1998
Additional Material:
8 Ill.
Type of Medium:
Electronic Resource
Permalink
