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  • Chemistry  (1)
  • air-water surface  (1)
  • analysis of libraries  (1)
  • asymmetric surfaces  (1)
  • 1
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    Thermal Processing of Packaged Foods (2008)
    Boston, MA : Springer
    Details
    Keywords: Chemistry ; Food science
    ISBN: 9780387722504
    URL: https://doi.org/10.1007/978-0-387-72250-4
    Language: English
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  • 2
    Electronic Resource
    Electronic Resource
    Limitations of the Coupling of Amino Acid Mixtures for the Preparation of Equimolar Peptide Libraries (1997)
    Springer
    Molecular diversity 3 (1997), S. 43-60 
    Details
    ISSN: 1573-501X
    Keywords: analysis of libraries ; coupling of mixtures ; incomplete libraries ; peptide libraries ; positional scanning
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract The standard method of peptide library synthesisinvolves coupling steps in which a single amino acidis reacted with a mixture of resin-bound amino acids.The more recently described positional scanningstrategy (in which each position in the peptide sequence is occupied in turn by a single residue) isdifferent since it involves the coupling of mixturesof amino acids to mixtures of resin-bound amino acids.In the present study, we analyze the compoundsproduced under these conditions measuring couplingrates and amounts of formed products, using mainly UV,HPLC, LC/MS and MS/MS techniques. Our data do notpermit to conclude that the resulting libraries arecomplete. Indeed, our analytical data indicate that alarge part of the di-, tri- and tetrapeptidessynthesized with this method are not present in thefinal mixture. Although chemical compensation (inwhich poor coupling kinetics is compensated by alarger excess of the incoming amino acid) has beenthought to counterbalance these biases, ourexperiments show that the compensation method does nottake into account the crucial influence of theresin-bound amino acid and that even the dipeptidelibraries obtained in this way are far fromcompleteness. The present work provides strong evidence that the coupling of mixtures of amino acidsto resin-bound residues, which is required by thepositional scanning strategy, results in incompleteand/or non-equimolar libraries. It also clearlyconfirms that coupling rates in solid-phase peptidesynthesis are dependent on the nature of both theincoming and the immobilized amino acid.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1009602707067
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  • 3
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    Microscale Surface Tension and Its Applications (2021)
    MDPI - Multidisciplinary Digital Publishing Institute
    Details
    Publication Date: 2024-04-11
    Description: Building on advances in miniaturization and soft matter, surface tension effects are a major key to the development of soft/fluidic microrobotics. Benefiting from scaling laws, surface tension and capillary effects can enable sensing, actuation, adhesion, confinement, compliance, and other structural and functional properties necessary in micro- and nanosystems. Various applications are under development: microfluidic and lab-on-chip devices, soft gripping and manipulation of particles, colloidal and interfacial assemblies, fluidic/droplet mechatronics. The capillary action is ubiquitous in drops, bubbles and menisci, opening a broad spectrum of technological solutions and scientific investigations. Identified grand challenges to the establishment of fluidic microrobotics include mastering the dynamics of capillary effects, controlling the hysteresis arising from wetting and evaporation, improving the dispensing and handling of tiny droplets, and developing a mechatronic approach for the control and programming of surface tension effects. In this Special Issue of Micromachines, we invite contributions covering all aspects of microscale engineering relying on surface tension. Particularly, we welcome contributions on fundamentals or applications related to:Drop-botics: fluidic or surface tension-based micro/nanorobotics: capillary manipulation, gripping, and actuation, sensing, folding, propulsion and bio-inspired solutions; Control of surface tension effects: surface tension gradients, active surfactants, thermocapillarity, electrowetting, elastocapillarity; Handling of droplets, bubbles and liquid bridges: dispensing, confinement, displacement, stretching, rupture, evaporation; Capillary forces: modelling, measurement, simulation; Interfacial engineering: smart liquids, surface treatments; Interfacial fluidic and capillary assembly of colloids and devices; Biological applications of surface tension, including lab-on-chip and organ-on-chip systems. We expect novel as well as review contributions on all aspects of surface tension-based micro/nanoengineering. In line with Micromachines' policy, we also invite research proposals that introduce ideas for new applications, devices, or technologies.
    Keywords: TA1-2040 ; T1-995 ; electrodynamic screen ; soft tissue ; microstructure ; mist capillary self-alignment ; droplet ; lab-on-a-chip ; mixing ; nanoprecipitation ; asymmetric surfaces ; gecko setae ; oil-water interface ; non-invasive control ; self-cleaning surface ; corrosive resistance ; micropipette-technique ; hydrophobic ; wettability gradient ; lung-surfactants ; hydrophilic ; dynamic ; vibrations ; superhydrophobic ; microasssembly ; adsorption ; wetting ; photochemical reaction ; contact line oscillation ; 355 nm UV laser ; capillary ; computational fluid dynamics ; bearing ; solutal Marangoni effect ; relaxation oscillations ; superhydrophilic ; microtexture melting ; rigid gas permeable contact lenses ; hydrophilic/superhydrophobic patterned surfaces ; polydimethylsiloxane (PDMS) replication ; microfabrication ; actuation ; droplet transport ; “droplet-interface-bilayers” ; microfluidics ; electrosurgical scalpels ; continuous-flow reactor ; air-water surface ; micromanufacturing ; surface treatment ; liquid bridge ; stereolithography ; super-hydrophobic ; two-phase flow ; hot drop ; durable ; insoluble lipids ; anti-sticking ; smart superhydrophobic surface ; droplet manipulation ; “black lipid films” ; condensation ; pick-and-place ; wettability ; gas-microbubbles ; soft robotics ; capillary pressure ; superomniphobic ; self-lubricating slippery surface ; electrowetting ; soluble surfactant ; anisotropic ratchet conveyor ; Nasturtium leaf ; droplets ; photoresponsible surfactant ; two-photon polymerization ; contact angle ; adhesion ; transport ; pick and place ; surface tension ; oil-microdroplets ; micromanipulation ; laser die transfer ; capillary gripper ; equilibrium ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology
    Language: English
    Format: application/octet-stream
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