ISSN:
0009-2940
Keywords:
Chemistry
;
Inorganic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Description / Table of Contents:
Microbiological Reduction of 3-Keto-19-nor-5(10)-ene Steroids to the Corresponding 3-Hydroxy-compounds17β-Hydroxy-19-nor-androst-5(10)-ene-3-one is reduced microbiologically to mixtures of 3α. 17β-and 3β. 17β-dihydroxy-19-nor androst-5(10)-ene. A preferred reduction to the 3β-hydroxy structure is possible by means of special yeasts. By the same strains different 3β-hydroxy-5(10)-ene structures are prepared from the corresponding 3-keto-substrates.
Notes:
17β-Hydroxy-19-nor-androsten-(5(10))-on-(3) wird mikrobiologisch zu Gemischen von 3α.17β-und 3β. 17β-Dihydroxy-19-nor-androsten-(5(10)) reduziert. Mit speziellen Hefen ist eine Reduktion überwiegend zur 3β-Hydroxy-Struktur möglich. Mit den gleichen Stämmen wurden unterschiedliche 3β-Hydroxy-5(10)-en-Strukturen aus weiteren entsprechenden 3-Keto-Substraten dargestellt.
Additional Material:
3 Tab.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/cber.19701030232
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