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  • Chemistry  (3)
  • Interventional Radiology.  (1)
  • Life and Medical Sciences  (1)
  • Lipoprotein binding  (1)
  • 1
    Keywords: Nervous system Surgery. ; Nervous system Radiography. ; Oncology. ; Medical physics. ; Neurology . ; Interventional radiology. ; Neurosurgery. ; Neuroradiology. ; Oncology. ; Medical Physics. ; Neurology. ; Interventional Radiology.
    Description / Table of Contents: Creating the Future -- CyberKnife Warfare in America: Battles at the Border Between Neurosurgery and Radiation Oncology -- The CyberKnife Robotic Radiosurgery System -- The Target Locating System for CyberKnife NeuroRadiosurgery -- Treatment Planning -- Small Field Dosimetry -- Quality Control -- Morphological Imaging -- Functional Imaging -- Diffusion Tensor Imaging (DTI) tractography -- Metabolic Imaging -- Radiobiology of Radiosurgery and Hypofractionated Treatments -- Organs at Risk (OAR) Tolerance in Hypofractionated Radiosurgery -- Brain Metastasis: Therapeutic, Diagnostic and Strategic Considerations -- Brain Metastasis: The Experience of the Burdenko Institute of Neurosurgery -- Multiple Brain Metastases -- Large Metastases and Tumor Bed -- Parasagittal and Convexity Meningiomas -- Skull Base Meningiomas -- High Grade Meningiomas and Hemagiopericytomas -- Perioptic Meningiomas -- Optic Nerve Sheath Meningiomas -- Vestibular Schwannomas -- Large Vestibular Schwannomas -- Pituitary Adenomas -- Craniopharyngiomas -- Malignant Gliomas -- Pilocytic Astrocytomas -- Pineal Tumors -- Reirradiation of Skull Base Tumors -- Chordomas and Chondrosarcomas -- Paragangliomas of Head and Neck -- Paragangliomas: a case series from Burdenko Institute -- Brainstem Tumors -- Uveal Melanoma -- Pediatric Radiosurgery -- Immunotherapy and Radiosurgery -- Spinal Metastases -- Reirradiation of Spinal Metastases -- Benign Spinal Tumors -- Intradural Spinal Lesions -- Cerebral Arteriovenous Malformations -- Large Arteriovenous Malformations -- Cerebral Cavernous Malformations -- Dural Arteriovenous Fistulas -- Cavernous Sinus Hemangiomas -- Trigeminal Neuralgia -- Movement Disorders -- Epilepsy -- Psychiatric/Behavioral Disorders. .
    Abstract: This book is a practical guide on image-guided robotic (CyberKnife®) radiosurgery of the brain and the spine. The volume introduces the radiosurgical community to the potential of image-guidance in the treatment of neurosurgical diseases including neuro-oncological, vascular and functional disorders. Principles of image-guided radiosurgery, including physics and radiobiology are considered. Each chapter provides a critical review of the literature and analyses of several aspects to offer an assessment of single and hypofractionated treatments. Based on the authors’ experience, tables or summaries presenting the treatment approaches and associated risks are included as well. Providing a practical guide to define the selection of dose, fractionation schemes, isodose line, margins, imaging, constraints to the structures at risk will support safe practice of neuroradiosurgery. This book aims to shed new light on the treatment of neoplastic and non-neoplastic diseases of the central nervous system using the CyberKnife® image-guided robotic radiosurgery system. It will be adopted by neurosurgery residents and neurosurgery consultants as well as residents in radiation oncology and radiation oncologists; medical physicists involved in radiosurgery procedures may also benefit from this book. .
    Type of Medium: Online Resource
    Pages: XVI, 588 p. 147 illus., 120 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030506681
    DDC: 617.48
    Language: English
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  • 2
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Biochimica et Biophysica Acta (BBA)/Lipids and Lipid Metabolism 713 (1982), S. 300-314 
    ISSN: 0005-2760
    Keywords: (Rabbit hepatocyte) ; HDL ; LDL ; Lipoprotein binding
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Medicine , Physics
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Cellular Physiology 159 (1994), S. 281-294 
    ISSN: 0021-9541
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: We have examined the effect of ethacrynic acid on mitochondrial morphology and distribution as well as on cellular toxicity in cultured human fibroblasts, African Green Monkey B-SC-1 kidney cells, and Chinese hamster ovary cells. Treatment of the above cells with 66 μM ethacrynic acid causes no reduction in cell viability after 2 h but is cytotoxic upon prolonged (6-7 days) exposure. Ethacrynic acid treatment for up to 2 h is found to cause novel shape changes and redistribution of mitochondria, as assessed by immunofluorescence and electron microscopy. Early effects include the transient formation of a mitochondrial reticulum involving the majority of mitochondria, and these reticula are aligned along microtubules. At later times within 2 h, mitochondrial distributions become disoriented (show no association with microtubules), and an aggregation and final positioning of mitochondria around the nucleus is observed. Whole mount electron microscopy shows that mitochondria in treated cells increase in length and form junctions, indicating reticula result from mitochondrial fusion. Electron microscopy of sections through ethacrynic acid induced reticula demonstrates structural continuity in mitochondria at branch points and the presence of regular cristae. Staining of endoplasmic reticulum and mitochondria in intact cells with the cyanine dye 3,3′-dihexyloxacarbocyanine iodide provides evidence of concurrent aggregation of endoplasmic reticulum. Rhodamine 123 staining of living cells followed by immunofluorescent labeling of mitochondria in the same cells indicates that all mitochondria retain a transmembrane potential during the druginduced shape changes and redistributions. The described effects of ethacrynic acid on mitochondrial morphology as well as on cellular toxicity are completely prevented by 0.5 mM dithiothreitol, indicating that ethacrynic acid is acting as a sulfhydryl reagent to produce the observed effects. The above observations also indicate that ethacrynic acid effects on mitochondrial morphology are an early event in the drug-induced cytotoxicity. The generation of varied mitochondrial morphologies by fusion and fission of mitochondria and its modulation by agents such as ethacrynic acid are discussed. © 1994 wiley-Liss, Inc.
    Additional Material: 10 Ill.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Berichte der deutschen chemischen Gesellschaft 66 (1933), S. 762-765 
    ISSN: 0365-9631
    Keywords: Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Berichte der deutschen chemischen Gesellschaft 65 (1932), S. 553-560 
    ISSN: 0365-9631
    Keywords: Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Berichte der deutschen chemischen Gesellschaft 69 (1936), S. 811-818 
    ISSN: 0365-9631
    Keywords: Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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