ISSN:
0570-0833
Schlagwort(e):
Glutamine synthetase
;
Enzymes
;
Chemistry
;
General Chemistry
Quelle:
Wiley InterScience Backfile Collection 1832-2000
Thema:
Chemie und Pharmazie
Notizen:
A highly sophisticated mechanism for the regulation of glutamine metabolism in Escherichia coli involves the modification of the enzyme glutamine synthetase by the covalent attachment and release of adenylyl residues. Separate enzymes catalyze the adenylylation and deadenylylation reactions, and these enzymes are reciprocally controlled by the state of nitrogen nutrition of the cell. The resultant structural alterations in glutamine synthetase enable it to change its catalytic potential greatly in response to varying cellular demands, in order to maintain nitrogen homeostasis.
Zusätzliches Material:
7 Ill.
Materialart:
Digitale Medien
URL:
http://dx.doi.org/10.1002/anie.197006701
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