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Effects of chemical chaperones on {alpha}-synuclein [Biophysics and Computational Biology] (2012)

Ferreon, A. C. M., Moosa, M. M., Gambin, Y., Deniz, A. A.

National Academy of Sciences

In: PNAS - Proceedings of the National Academy of Sciences

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Publication Date: 2012-10-31

Description: Protein structure and function depend on a close interplay between intrinsic folding energy landscapes and the chemistry of the protein environment. Osmolytes are small-molecule compounds that can act as chemical chaperones by altering the environment in a cellular context. Despite their importance, detailed studies on the role of these chemical...

Keywords: Chemical Physics of Protein Folding Special Feature

Print ISSN: 0027-8424

Electronic ISSN: 1091-6490

Topics: Biology , Medicine , Natural Sciences in General

Published by National Academy of Sciences

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