Publication Date:
1986-04-11
Description:
Synapses develop concurrently and at identical rates in different layers of the visual, somatosensory, motor, and prefrontal areas of the primate cerebral cortex. This isochronic course of synaptogenesis in anatomically and functionally diverse regions indicates that the entire cerebral cortex develops as a whole and that the establishment of cell-to-cell communication in this structure may be orchestrated by a single genetic or humoral signal. This is in contrast to the traditional view of hierarchical development of the cortical regions and provides new insight into the maturation of cortical functions.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Rakic, P -- Bourgeois, J P -- Eckenhoff, M F -- Zecevic, N -- Goldman-Rakic, P S -- EY02593/EY/NEI NIH HHS/ -- MH38546/MH/NIMH NIH HHS/ -- NS22807/NS/NINDS NIH HHS/ -- New York, N.Y. -- Science. 1986 Apr 11;232(4747):232-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/3952506" target="_blank"〉PubMed〈/a〉
Keywords:
Animals
;
Cerebral Cortex/growth & development/*physiology
;
Macaca mulatta
;
Motor Cortex/growth & development/physiology
;
Somatosensory Cortex/growth & development/physiology
;
Synapses/*physiology
;
Visual Cortex/growth & development/physiology
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
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