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  • Caerulein  (1)
  • intestinal perfusion  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Factors influencing the intestinal phase of pancreatic exocrine secretion in the turkey (1995)
    Springer
    Cellular and molecular life sciences 51 (1995), S. 249-251 
    Details
    ISSN: 1420-9071
    Keywords: Exocrine pancreatic secretion ; intestinal perfusion ; atropine ; turkey
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract The present study was done to investigate the factors regulating the intestinal phase of exocrine pancreatic secretion in the turkey. The intestine of turkeys equipped with pancreatic fistulas was perfused with peptone solution, fat emulsion and hydrochloric acid (HCl), and pancreatic flow and protein output were measured. Neither peptone solution nor fat emulsion had any effects on pancreatic secretion. HCl enhanced the flow rate of pancreatic juice but not protein output. To clarify the neural mechanism of this phenomenon, the vagal postganglionic blocker atropine was continuously infused and pancreatic secretion in response to intestinal HCl was measured. Atropine completely suppressed both pancreatic flow and protein output. It is suggested that the avian intestinal phase of pancreatic secretion is mainly controlled by cholinergic action though HCl stimulation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01931106
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  • 2
    Electronic Resource
    Electronic Resource
    Endogenous cholecystokinin is not a major regulator of food intake in the chicken (1994)
    Springer
    Journal of comparative physiology 164 (1994), S. 425-429 
    Details
    ISSN: 1432-136X
    Keywords: Cholecystokinin ; Caerulein ; Chicken food intake ; Devazepide ; Amylase secretion
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract This study investigated whether or not endogenous cholecystokinin exerts satiety effects in chickens. After several doses (0, 1, 2 and 4 μg·kg body weight-1) of intravenous injection of caerulein, the bile flow was increased in a dose-dependent fashion. However, the pharmacological level of caerulein failed to suppress the food intake of chickens. Two potent stimulators of endogenous cholecystokinin, i.e., soybean trypsin inhibitor and phenylalanine were administered to chickens before feeding and food intake was determined over 2 h. The soybean trypsin inhibitor and phenylalanine did not alter food intake. Devazepide, a cholecystokinin-A receptor antagonist, significantly decreased amylase release from the dispersed chicken pancreatic acini stimulated by caerulein. However, devazepide did not improve food intake of the chicken. The results obtained suggest that endogenous cholecystokinin may not act as a satiety signal in chickens.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00714578
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