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    Evolutionary tree reconstruction (1990)
    In:  CASI
    Details
    Publication Date: 2019-06-28
    Description: It is described how Minimum Description Length (MDL) can be applied to the problem of DNA and protein evolutionary tree reconstruction. If there is a set of mutations that transform a common ancestor into a set of the known sequences, and this description is shorter than the information to encode the known sequences directly, then strong evidence for an evolutionary relationship has been found. A heuristic algorithm is described that searches for the simplest tree (smallest MDL) that finds close to optimal trees on the test data. Various ways of extending the MDL theory to more complex evolutionary relationships are discussed.
    Keywords: COMPUTER PROGRAMMING AND SOFTWARE
    Type: NASA-CR-188862 , NAS 1.26:188862 , RIACS-TR-90-27
    Format: application/pdf
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