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  • Brevetoxins  (1)
  • LC-MS  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 16 (1993), S. 85-89 
    ISSN: 0935-6304
    Keywords: Fullerenes ; Liquid chromatography ; Mass Spectrometry ; LC-MS ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Fullerene-rich soot generated by resistive heating of graphite has been gently extracted with toluene, in order to remove some C60 and C70 compounds, followed by extraction with boiling 1,2,4-trichlorobenzene at 214°C. After filtration and removal of the solvent, the residue was re-dissolved in dichloromethane and characterized by non-aqueous reversed phase liquid chromatography coupled on-line with atmospheric pressure chemical ionization mass spectrometry. Several novel fullerenes were detected, including C72, C80, C86, and C88 as well as other fullerenes up to C108 and higher. The results indicate that chromatographic separation of large fullerene molecules can be achieved with low boiling point solvents and conventional liquid chromatographic techniques.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
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  • 2
    Publication Date: 2022-05-26
    Description: Author Posting. © The Author(s), 2011. This is the author's version of the work. It is posted here by permission of Elsevier B.V. for personal use, not for redistribution. The definitive version was published in Desalination 293 (2012): 1-6, doi:10.1016/j.desal.2012.02.014.
    Description: Over the last several decades, countries throughout the world have experienced an escalating and worrisome trend in the incidence of harmful algal blooms (HABs). A concern is that highly potent algal toxins might be retained in the treated water, posing a threat to human health. Seawater contaminated with saxitoxins, domoic acid, okadaic acid, and brevetoxins was desalinated using small (〈100 mL capacity) reverse osmosis and distillation equipment. Analyses of desalinated water samples indicated efficient removal of the four toxins to greater than 99%, except brevetoxins for which some carryover was observed during distillation. Hypochlorite concentrations of 4 ppm or higher were sufficient to react with all of the saxitoxins, domoic acid and okadaic acid in the samples that contained initial toxin concentrations up to 1,250 ng.mL-1 . Brevetoxins appeared to be unaffected in experiments in which the toxins were exposed to up to 30 ppm hypochlorite in seawater at 35 °C for 60 min. These results and their implications in terms of desalination plant design and operation are discussed.
    Description: This work was also supported in part by the Woods Hole Center for Oceans and Human Health (NSF Grants OCE-0430724 and OCE-0911031; NIEHS Grant P50ES012742-01) and Effects of Inhaled Florida Red Tide Brevetoxins (NIH Grant P01 ES010594-09).
    Keywords: HAB Toxins ; Red tide ; Detoxification ; Saxitoxins ; Domoic acid ; Okadaic acid ; Brevetoxins
    Repository Name: Woods Hole Open Access Server
    Type: Preprint
    Format: application/pdf
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