Publication Date:
2012-08-11
Description:
Selective attention mechanisms route behaviorally relevant information through large-scale cortical networks. Although evidence suggests that populations of cortical neurons synchronize their activity to preferentially transmit information about attentional priorities, it is unclear how cortical synchrony across a network is accomplished. Based on its anatomical connectivity with the cortex, we hypothesized that the pulvinar, a thalamic nucleus, regulates cortical synchrony. We mapped pulvino-cortical networks within the visual system, using diffusion tensor imaging, and simultaneously recorded spikes and field potentials from these interconnected network sites in monkeys performing a visuospatial attention task. The pulvinar synchronized activity between interconnected cortical areas according to attentional allocation, suggesting a critical role for the thalamus not only in attentional selection but more generally in regulating information transmission across the visual cortex.〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3714098/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉 〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3714098/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Saalmann, Yuri B -- Pinsk, Mark A -- Wang, Liang -- Li, Xin -- Kastner, Sabine -- R01 EY017699/EY/NEI NIH HHS/ -- R21 EY021078/EY/NEI NIH HHS/ -- New York, N.Y. -- Science. 2012 Aug 10;337(6095):753-6. doi: 10.1126/science.1223082.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Princeton Neuroscience Institute, Princeton University, Princeton, NJ 08544, USA. saalmann@princeton.edu〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/22879517" target="_blank"〉PubMed〈/a〉
Keywords:
Action Potentials
;
Animals
;
*Attention
;
Brain Mapping
;
*Cortical Synchronization
;
Cues
;
Diffusion Tensor Imaging
;
Macaca fascicularis
;
Male
;
Nerve Net/*physiology
;
Neurons/physiology
;
Pulvinar/cytology/*physiology
;
Space Perception
;
Visual Cortex/*physiology
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
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