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  • 1
    Electronic Resource
    Electronic Resource
    Polymerase chain Reaction in molecular biotechnology; appropriate technology for developing countries (1996)
    Springer
    World journal of microbiology and biotechnology 12 (1996), S. 467-471 
    Details
    ISSN: 1573-0972
    Keywords: Biotechnology ; developing countries ; PCR
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Abstract The product of the Polymerase Chain Reaction (PCR) may be generically suitable for four types of investigations: Discovery PCR, Analytical PCR, Modification by PCR, and Synthetic PCR. Despite the potential problem of contamination with extraneous DNA, PCR is relatively simple and inexpensive, and thereby offers opportunities for laboratories from smaller or developing countries to invest limited resources in competitive global research and development, or in applications of economic and social value in health, agriculture and other sectors.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00419459
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  • 2
    Electronic Resource
    Electronic Resource
    Detection and quantitation of the fetal hemoglobin variant Hb F-Malta-I in adults (1977)
    Springer
    Biochemical genetics 15 (1977), S. 915-923 
    Details
    ISSN: 1573-4927
    Keywords: radioimmunoassay ; hemoglobin F variants ; hemoglobinopathies ; γ chain loci
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Abstract A variant of fetal hemoglobin (Hb F-Malta-I) has been detected and quantitated in adult blood with a sensitive radioimmunoassay employing monospecific anti-sera. The concentration of Hb F-Malta-I was 0.002–0.05%, with an average value of 0.011%. The ratio of Hb F-Malta-I/Hb F in adults was about 4.8%, compared to a ratio of about 27% in the newborn. Since the F-Malta-I variant is a product of a mutated Gγ locus, which is one of the nonallelic structural genes directing the γ chain synthesis, its presence in blood of adults shows that the synthesis of this gene is not completely suppressed after birth, as was previously suggested.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00483988
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