Keywords:
Immunology.
;
Medicine Research.
;
Biology Research.
;
Allergy.
;
Immunology.
;
Biomedical Research.
;
Allergology.
Description / Table of Contents:
B cell development and maturation -- B cell receptor signalling -- Involvement of reactive oxygen species (ROS) in BCR signaling as a second messenger -- Germinal center reaction -- Memory B cells in local and systemic sites -- Regulation of plasma cell differentiation -- Regulation of humoral immune responses and B cell tolerance by the IgM Fc receptor -- Regulatory B cells -- Diversified IgA-bacteria interaction in gut homeostasis -- Primary antibody deficiencies -- B cell-mediated autoimmune diseases -- B cell lymphomas.
Abstract:
This book contains twelve chapters contributed by prestigious international experts who are at the forefront of B cell research, and aims to provide a cutting-edge and comprehensive overview of all aspects of B cells, including B cell development, maturation and activation, germinal center reaction, memory and plasma cell differentiation, and antibody-mediated positive and negative regulation of humoral immune responses. There are also three chapters describing human diseases caused by B cell abnormalities, including primary antibody deficiencies, autoimmune diseases, and B cell malignancies. We hope that this book will become a standard and routine reference for both basic researchers and clinicians.
Type of Medium:
Online Resource
Pages:
XII, 181 p. 35 illus., 30 illus. in color.
,
online resource.
Edition:
1st ed. 2020.
ISBN:
9789811535321
Series Statement:
Advances in Experimental Medicine and Biology, 1254
URL:
https://doi.org/10.1007/978-981-15-3532-1
DOI:
10.1007/978-981-15-3532-1
DDC:
571.96
Language:
English
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