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  • 1
    Electronic Resource
    Electronic Resource
    Dendritic and Synaptic Effects in Systems of Coupled Cortical Oscillators (1998)
    Springer
    Journal of computational neuroscience 5 (1998), S. 315-329 
    Details
    ISSN: 1573-6873
    Keywords: synchrony ; cortical oscillators ; phase model ; synaptic effects ; dendritic delay
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science , Medicine , Physics
    Notes: Abstract We explore the influence of synaptic location and form on the behavior of networks of coupled cortical oscillators. First, we develop a model of two coupled somatic oscillators that includes passive dendritic cables. Using a phase model approach, we show that the synchronous solution can change from a stable solution to an unstable one as the cable lengthens and the synaptic position moves further from the soma. We confirm this prediction using a system of coupled compartmental models. We also demonstrate that when the synchronous solution becomes unstable, a bifurcation occurs and a pair of asynchronous stable solutions appear, causing a phase lag between the cells in the system. Then using a variety of coupling functions and different synaptic positions, we show that distal connections and broad synaptic time courses encourage phase lags that can be reduced, eliminated, or enhanced by the presence of active currents in the dendrite. This mechanism may appear in neural systems where proximal connections could be used to encourage synchrony, and distal connections and broad synaptic time courses could be used to produce phase lags that can be modulated by active currents.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1008839112707
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  • 2
    Electronic Resource
    Electronic Resource
    The development of a process for recovering nucleotides from Bakers' yeast (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    Biotechnology and Bioengineering 5 (1963), S. 221-230 
    Details
    ISSN: 0006-3592
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: A process has been developed giving over-all yields of about 50%: which could be increased to about 80% with higher material costs and processing time. The preferred method of recovering nucleotides from the cytoplasm has been thermal extraction by means of a heat exchanger followed by filtration, protein precipitation, and carbon adsorption. The concentrated eluate from the carbon is absorbed onto Dowex 1 ion-exchange resin, and groups of nucleotides are removed by pH-defined eluents and recovered by a second carbon adsorption. Finally, standard ion-exchange resolutions have been used to recover individual nucleotides. Other biochemicals in the extract have been investigated, and preliminary work has been done on the combination of nucleotide extraction with the recovery of nucleic acids from the residual cells.
    Additional Material: 3 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/bit.260050307
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  • 3
    Electronic Resource
    Electronic Resource
    The Role of Axonal Delay in the Synchronization of Networks of Coupled Cortical Oscillators (1997)
    Springer
    Journal of computational neuroscience 4 (1997), S. 161-172 
    Details
    ISSN: 1573-6873
    Keywords: axonal delay ; cortical oscillators ; phase ; synchrony ; coupled oscillators
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science , Medicine , Physics
    Notes: Abstract Coupled oscillator models use a single phase variable to approximate the voltage oscillation of each neuron during repetitivefiring where the behavior of the model depends on the connectivityand the interaction function chosen to describe the coupling. Weintroduce a network model consisting of a continuum of theseoscillators that includes the effects of spatially decaying coupling and axonal delay. We derive equations for determining the stability of solutions and analyze the network behavior for two different interaction functions. The first is a sine function, and the second is derived from a compartmental model of a pyramidal cell.In both cases, the system of coupled neural oscillators can undergo a bifurcation from synchronous oscillations to waves.The change in qualitative behavior is due to the axonal delay,which causes distant connections to encourage a phase shift between cells. We suggest that this mechanism could contribute to the behavior observed in several neurobiological systems.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1008843412952
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  • 4
    Electronic Resource
    Electronic Resource
    Editorial (1985)
    New York, NY [u.a.] : Wiley-Blackwell
    Cell Biochemistry and Function 3 (1985), S. 1-1 
    Details
    ISSN: 0263-6484
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/cbf.290030102
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  • 5
    Electronic Resource
    Electronic Resource
    Editorial (1983)
    New York, NY [u.a.] : Wiley-Blackwell
    Cell Biochemistry and Function 1 (1983), S. 2-2 
    Details
    ISSN: 0263-6484
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/cbf.290010102
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  • 6
    Electronic Resource
    Electronic Resource
    Immobilised enzymes and cells. A. Roseveare, J. F. Kennedy, and J. M. S. Cabral. Adam Hilger: Bristol and Philadelphia, ix + 248 pages, £37.50. (1987). (1989)
    New York, NY [u.a.] : Wiley-Blackwell
    Cell Biochemistry and Function 7 (1989), S. 77-77 
    Details
    ISSN: 0263-6484
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/cbf.290070117
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  • 7
    Electronic Resource
    Electronic Resource
    The evaluation of a process for the preparation of co-enzyme A from yeast (1959)
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Biochemical and Microbiological Technology and Engineering 1 (1959), S. 217-228 
    Details
    ISSN: 0368-1467
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: A process is described for the extraction of co-enzyme A from dried yeast. It involves cold water extraction, charcoal adsorption followed by pyridine elution, preparation of an acetone power, co-precipitation as the double cuprous complex with glutathione and removal of the glutathione by means of an ion exchange resin.Improvements over previous processes include use of drum dried yeast plus cold extraction resulting in easy filtration and increase of throughput by a factor of three to five, together with the elimination of the ion exchange step formerly thought necessary to remove zine before the co-precipitation stage. Under the best conditions yields represent 30% recovery of the co-enzyme A in the yeast, the product being 90% pure.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jbmte.390010208
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  • 8
    Electronic Resource
    Electronic Resource
    Biochemical preparations, Volume 6; Ed. Carl S. Vestling. New York, John Wiley & Sons, Inc.; London, Chapman & Hall, Ltd. IX and 105 pp. 42/- (1959)
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Biochemical and Microbiological Technology and Engineering 1 (1959), S. 244-244 
    Details
    ISSN: 0368-1467
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jbmte.390010212
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  • 9
    Electronic Resource
    Electronic Resource
    1st international meeting on cell biochemistry and function (1983)
    New York, NY [u.a.] : Wiley-Blackwell
    Cell Biochemistry and Function 1 (1983), S. 125-128 
    Details
    ISSN: 0263-6484
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/cbf.290010215
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