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  • 1
    ISSN: 1573-904X
    Keywords: antipyrine ; drug metabolism ; metabolic liver function ; hepatitis ; P-450 activities ; liquid chromatography
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract We describe a simplified and rapid liquid chromatographic determination of antipyrine clearance (CLAP) calculated from peak height ratios of drug/internal standard. Saliva or plasma was collected 24 hr after the oral administration of 1 g of antipyrine to the subject. A 25-µl aliquot of the sample is deproteinized with acetonitrile containing 3-nitrophenol (internal standard) and injected into a radial compression module equipped with a 10-µm, 8 mm × 10-cm C18 cartridge, using a 0.025 M aqueous solution of sodium acetate and acetonitrile (88.5:11.5). The minimum measurable concentration was 0.2 µg/ml. The obtained CLAP values in five healthy subjects and five patients with chronic liver disease coincided well (r 〉 0.9994) with those generated by the use of an established method. The antipyrine clearance in the healthy subjects ranged from 2.203 to 5.721 liters/hr, while in patients with chronic liver disease it was significantly (P 〈 0.0027) less (range, 0.544 to 1.103 liter/hr). We also determined antipyrine clearance in two of these subjects given lower doses of this drug and found that the dose has no significant impact on this parameter.
    Type of Medium: Electronic Resource
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  • 2
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    In:  osf@vti.bund.de | http://aquaticcommons.org/id/eprint/3644 | 1240 | 2012-11-09 13:43:47 | 3644 | Bundesforschungsanstalt für Fischerei
    Publication Date: 2021-06-28
    Description: Die Tagung setzte den während der vorigen Jahrestagung zu beobachtenden Kurs einer Schwerpunktverlagerung generell fort. Diese ist durch die stärkere Berücksichtigung des Vorsorgeansatzes im Fischereimanagement auf der Grundlage wissenschaftlicher Empfehlungen des ACFM (Management-Komiteefür Fischerei) des ICES gekennzeichnet. Damit traten die in der Vergangenheit fischereipolitisch dominierten nationalen Managementinteressen weitestgehend in den Hintergrund und trugen somit zu einer sachlichen Tagungsatmosphäre bei. Wichtigste Tagungsthemen waren die Ausnutzung der nationalen Quoten für 1997 und 1998 (1. Halbjahr), die Festlegung der zulässigen Gesamtfangmengen (TAC) für die internationalen Fischereien 1999, aber auch Strategien zur Nutzung der lebenden Ressourcen der Ostsee unter den Bedingungen des Vorsorgeansatzes im Fischereimanagement. An den Beratungen nahmen Ländervertreter und Experten Estlands, der EU, Lettlands, Polens und der Russischen Föderation sowie Beobachter des ICES (Internationaler Rat für Meeresforschung) und der HELCOM (Helsinki-Kommission) teil.
    Description: Johann Heinrich von Thünen-Institute, Federal Research Institute for Rural Areas, Forestry and Fisheries began publishing the Informationen aus der Fischereiforschung = Information on Fishery research in 2010.
    Keywords: Management ; Fisheries ; precaution ; fisheries management ; scientific advice ; TAC ; Baltic Sea
    Repository Name: AquaDocs
    Type: article , FALSE
    Format: application/pdf
    Format: application/pdf
    Format: 171-175
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  • 3
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    In:  http://aquaticcommons.org/id/eprint/3237 | 1240 | 2012-11-10 14:35:41 | 3237 | Bundesforschungsanstalt für Fischerei
    Publication Date: 2021-06-26
    Description: The introduction of a long-term management plan for the cod socks by the International Baltic Sea Fishery Commission (IBSFC) to ensure stable and high yields and to conserve the fish stocks of the Baltic demands certain conservation measures. One is the use of the Total Allowable Catches (TACs) based on precautionary approches. In addition the exploitation pattern and the selectivy of trawls shall be improved to increase the spawning stock biomass and to reduce the presently high discard rates. The contributation demonstrates by means of model calculations for the cod stock of the ICES Sub-divisions 22 to 24 ( Western Baltic ) the short- and long-term effects of an improvement of the trawl selectivity on stock size, yields and profit.
    Description: Johann Heinrich von Thünen-Institute, Federal Research Institute for Rural Areas, Forestry and Fisheries began publishing the Informationen aus der Fischereiforschung = Information on Fishery research in 2010.
    Keywords: Management ; Fisheries ; fisheries management ; scientific advice ; mesh selection ; economic yield ; trawl fishery ; cod ; Baltic Sea
    Repository Name: AquaDocs
    Type: article , FALSE
    Format: application/pdf
    Format: application/pdf
    Format: 19-24
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  • 4
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    In:  osf@vti.bund.de | http://aquaticcommons.org/id/eprint/3295 | 1240 | 2012-04-25 16:22:05 | 3295 | Bundesforschungsanstalt für Fischerei
    Publication Date: 2021-06-27
    Description: In 1998 the longtime series of the standardized bottom trawl surveys conducted in the western Baltic (ICES Sub-division (SD) 22 and 24 since 1978) during spring and autumn and also in the eastern Baltic (ICES Sub-division since 1993) during spring were continued. The results of the surveys as well as those of a sampling programme carried out on board of commercial cutters (mainly financed by an EU study project) and on the market, the investigation of the survival rate of the discards, and the landing statistics are the basis of the analysis of the German and international cod fishery in 1998. The German cod fishery was concentrated on the ICES SD 22 and 24 (total landings 9722 t). The total landings from the fishing grounds east off Bornholm, the traditional German fishing ground, amounted only to about 1270 t. The German cod quota was utilized at 64 %. The fishery in the ICES SD 22 and 24 was characterized by a discard rate of undersized cod of 13 %. That corresponds to about 7.3 million specimens of 0-group, one- and two-years-old youngfish, respectively. The total international cod landings of the Baltic amounted to 101 500 t. In comparison with 1997 (totallandings 129 600 t) the landing decreased by 23 %. The percentage utilization of the cod TAC (1998: 140 000 t) amounted to 74 % in 1998.
    Description: Johann Heinrich von Thünen-Institute, Federal Research Institute for Rural Areas, Forestry and Fisheries began publishing the Informationen aus der Fischereiforschung = Information on Fishery research in 2010.
    Keywords: Fisheries ; catch effort ; trawl fishery ; discards ; bycatch ; Baltic Sea
    Repository Name: AquaDocs
    Type: article , FALSE
    Format: application/pdf
    Format: application/pdf
    Format: 32-35
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  • 5
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    In:  osf@vti.bund.de | http://aquaticcommons.org/id/eprint/3318 | 1240 | 2012-11-09 13:44:52 | 3318 | Bundesforschungsanstalt für Fischerei
    Publication Date: 2021-06-27
    Description: Die Tagung fand in Warschau, dem Sitz des Sekretariats der IBSFC, statt. Arbeitsebenen der Tagung sind Plenarsitzungen und Sitzungen der beiden Ständigen Komitees „Regulierungsmaßnahmen“ und „Finanzen“. Die Plenarsitzungen und Sitzungen des Ständigen Komitees für Regulierungsmaßnahmen mit insgesamt 34 Tagungsordnungspunkten waren geprägt von der Analyse der nationalen Fischereien im Basiszeitraum, d.h. von der Ausnutzung der nationalen Quoten für 1996 und z.T. 1997, den Beratungen zum Fischereimanagement für 1998, aber auch vom Vorsorgeansatz im Fischereimanagement und den Auswirkungen der sogenannten Rio-Konferenz (UN-Konferenz über Umwelt und Entwicklung, Rio de Janeiro 1992) für den Ostseeraum.
    Description: Johann Heinrich von Thünen-Institute, Federal Research Institute for Rural Areas, Forestry and Fisheries began publishing the Informationen aus der Fischereiforschung = Information on Fishery research in 2010.
    Keywords: Management ; Fisheries ; conference proceeding ; Baltic Sea ; Regulations ; TAC ; scientific advice
    Repository Name: AquaDocs
    Type: article , FALSE
    Format: application/pdf
    Format: application/pdf
    Format: 53-55
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