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  • 1
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    Nucleoside synthesis under potentially prebiotic conditions. (1967)
    In:  Other Sources
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    Publication Date: 2011-08-12
    Description: Nucleoside synthesis under potentially prebiotic conditions
    Keywords: BIOSCIENCES
    Format: text
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    NASA TECHNICAL REPORTS
  • 2
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    Prebiotic activation processes. (1973)
    In:  Other Sources
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    Publication Date: 2011-08-16
    Description: Questions regarding the combination of amino acids and ribonucleotides to polypeptides and polynucleotides are investigated. Each of the reactions considered occurs in the solid state in plausible prebiotic conditions. Together they provide the basis for a unified scheme of amino acid and nucleotide activation. Urea, imidazole and Mg(++) are essential catalytic components of the reaction mixtures. However, these compounds could probably be replaced by other organic molecules.
    Keywords: BIOSCIENCES
    Type: Nature; 244; Aug. 17
    Format: text
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    NASA TECHNICAL REPORTS
  • 3
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    A possible step in the origin of the genetic code. (1972)
    In:  Other Sources
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    Publication Date: 2019-06-27
    Description: It is suggested that the earliest coding polynucleotides contained a high proportion of alternating sequences of purines and pyrimidines, and that these sequences coded for polypeptides in which hydrophobic and hydrophylic amino acids alternated. Structural properties of such alternating polypeptides are discussed.
    Keywords: BIOSCIENCES
    Type: Israel Journal of Chemistry; 10; 1972
    Format: text
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    NASA TECHNICAL REPORTS
  • 4
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    Prebiotic phosphorylation of thymidine at 65 C in simulated desert conditions. (1972)
    In:  Other Sources
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    Publication Date: 2019-06-27
    Description: The phosphorylation of thymidine is described for a variety of conditions at 65 C to demonstrate that the reaction could readily take place in deserts at the present time. This might be used as an indication that urea-phosphate mixtures could have been important as phosphorylating agents on the primitive earth. Reaction products were identified by comparing their chromatographic and electrophoretic mobilities with those of authentic materials and by enzymatic degradation. The results show that good yields of nucleotides are obtained when nucleosides are heated with urea-phospate mixtures at 65 C. Reactions proceed more rapidly at moderate humidities than in a stream of dry nitrogen. Occasional wetting results in even faster and more extensive reactions. There was no reaction for a mixture of urea and trimetaphosphate.
    Keywords: BIOSCIENCES
    Type: Nature; 237; May 19
    Format: text
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    NASA TECHNICAL REPORTS
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