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  • Geotechnical Engineering and Applied Earth Sciences.  (3)
  • Engineering Design.  (2)
  • Atomic and molecular structure and dynamics  (1)
  • Bcl-2  (1)
  • 1
    Online-Ressource
    Online-Ressource
    Singapore :Springer Nature Singapore :
    Schlagwort(e): Geotechnical engineering. ; Natural disasters. ; Engineering design. ; Civil engineering. ; Sustainability. ; Geotechnical Engineering and Applied Earth Sciences. ; Natural Hazards. ; Engineering Design. ; Civil Engineering. ; Sustainability.
    Kurzfassung: This book provides a new framework for analysis of slope nonlinear stochastic seismic dynamic response based on the new theoretical tool of stochastic dynamics. The coupling effects of uncertainty of geological parameters, strong dynamic nonlinearity, and randomness of ground motion are considered in the process of the seismic dynamic stability assessment of slope. In this book, an intensity frequency non-stationary stochastic ground motion model based on time-domain stochastic process description is preliminarily established to characterize the randomness of earthquakes. The spatial distribution random field model of geotechnical parameters is established to describe the time-space variability of geotechnical parameters. Based on the basic theory of stochastic dynamics, the seismic stability performance evaluation method of slope is established. The slope seismic dynamic model test based on large complex shaking table is performed to verify and modify the proposed framework and method. This book sheds new light on the development of nonlinear seismic stochastic dynamics and seismic design of slope engineering. .
    Materialart: Online-Ressource
    Seiten: XXII, 155 p. 86 illus., 79 illus. in color. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9789811696978
    DDC: 624.151
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 2
    Online-Ressource
    Online-Ressource
    Singapore :Springer Nature Singapore :
    Schlagwort(e): Geotechnical engineering. ; Natural disasters. ; Engineering design. ; Engineering geology. ; Sustainability. ; Geotechnical Engineering and Applied Earth Sciences. ; Natural Hazards. ; Engineering Design. ; Geoengineering. ; Sustainability.
    Beschreibung / Inhaltsverzeichnis: Introduction -- Terms and Notations -- Performance-based Seismic Design of Slope -- Seismic Ground Motion Excitations for Slope Seismic Dynamic Performance Design and Assessment -- Deterministic Analysis Methods for Slope Seismic Dynamic Response -- Probabilistic Performance-based Seismic Design and Assessment for Slope Engineering -- Case Study -- Conclusions and Prospects.
    Kurzfassung: This book provides a new design and evaluation framework based on slope Stochastic Dynamics theory to probabilistic seismic performance for slope engineering. For the seismic dynamic stability safety of slope, it shifts from deterministic seismic dynamic analysis to quantitative analysis based on nonlinear stochastic dynamics, that is, from qualitative to the description of stochasticity of earthquake excitation that meet the needs in related design specification and establish a performance standard. In the nonlinear dynamic time history analysis of slope subjected to seismic ground motion, the term “randomness” is used to express the uncertainty in the intensity and frequency of earthquake excitation for slope engineering dynamic seismic performance. It mainly includes seismic design fortification standard, corresponding ground motion excitation, performance index threshold, and slope deterministic nonlinear seismic dynamic response. Even more than that, the seismic dynamic large deformation approaches of the whole process and comprehensive analysis for flow analysis after slope instability failure. Eventually, the probabilistic seismic dynamic performance of the slope engineering will be characterized by nonlinear dynamic reliability.
    Materialart: Online-Ressource
    Seiten: XVII, 134 p. 51 illus., 46 illus. in color. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9789811991837
    DDC: 624.151
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 3
    Online-Ressource
    Online-Ressource
    Singapore :Springer Nature Singapore :
    Schlagwort(e): Geotechnical engineering. ; Natural disasters. ; Fire prevention. ; Buildings Protection. ; Geotechnical Engineering and Applied Earth Sciences. ; Natural Hazards. ; Fire Science, Hazard Control, Building Safety.
    Beschreibung / Inhaltsverzeichnis: Natural Slope -- Embankment -- Cut -- Falling Rocks -- Sabo Facility -- River Levee -- Retaining Wall -- Snow Shed/Rock Shed -- Tunnel -- Pavement -- Slab -- Steel Bridge -- Concrete Bridge -- Box Culvert -- Waterworks and Sewage.
    Kurzfassung: This book explains in an easy-to-understand manner the “check” points to keep in mind when inspecting various social infrastructure structures. It is put together in a way that not only engineers who are on the front line of maintenance and management but also engineers who are not normally involved in maintenance and management of social infrastructures as well as general public can understand the importance of social infrastructure inspection work.
    Materialart: Online-Ressource
    Seiten: XIII, 141 p. 151 illus. , online resource.
    Ausgabe: 1st ed. 2021.
    ISBN: 9789811588280
    DDC: 624.151
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 4
    Digitale Medien
    Digitale Medien
    Springer
    Journal of biomedical science 5 (1998), S. 185-191 
    ISSN: 1423-0127
    Schlagwort(e): TGF-β ; Bcl-2 ; Apoptosis ; Antioxidative enzyme ; Reactive oxygen species
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Medizin
    Notizen: Abstract Transforming growth factor-β (TGF-β) has been shown to induce apoptosis on normal hepatocytes and hepatoma cells both in vitro and in vivo. However, how the TGF-β induces apoptosis is still not clear. We examined the expression of anti-apoptosis proteins and sensitivity to TGF-β in three well differentiated human hepatoma cell lines. Two TGF-β sensitive cell lines Hep3B and HuH7 totally lacked Bcl-2. In contrast, the TGF-β resistant HepG2 cells expressed a substantial amount of Bcl-2. All three cell lines expressed equal amounts of Bcl-XL, Bcl-XS and Bax. Overexpression of Bcl-2 in Hep3B and HuH7 cells protected them from TGF-β-induced apoptosis. TGF-β treatment increased intracellular peroxide production and suppressed the expression of glutathione-S-transferase in the Hep3B cells, and these effects were partially suppressed by the overexpression of Bcl-2. These results suggest that Bcl-2 may protect cell from TGF-β-F-induced apoptosis by interfering TGF-β generated signals leading to induce reactive oxygen species production.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 5
    Publikationsdatum: 2018-03-27
    Beschreibung: Author(s): Yi-Jan Huang, Yu-Chan Guan, Yao-Chin Huang, Te-Hwei Suen, Jin-Long Peng, Li-Bang Wang, and Jow-Tsong Shy The transition frequency between the 2 1 S 0 and 3 1 D 2 states of 4 He atoms is measured by two-photon spectroscopy with an accuracy more than one order of magnitude higher than in previous experiments. The determination of some related transition frequencies provides a good test against the theoretically calculated energy levels. [Phys. Rev. A 97, 032516] Published Mon Mar 26, 2018
    Schlagwort(e): Atomic and molecular structure and dynamics
    Print ISSN: 1050-2947
    Digitale ISSN: 1094-1622
    Thema: Physik
    Standort Signatur Erwartet Verfügbarkeit
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