ISSN:
1741-0444
Keywords:
Artificial kidney
;
Electric analogue model
;
Extracorporal blood circulation
;
Single-needle
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Chemistry and Pharmacology
,
Medicine
Notes:
Abstract Using an electric analogue model, the flow conditions (the progress over time of blood pressure and blood flow) within the single-needle extracorporal bloodcirculatory system of an artificial kidney are investigated. Two different arrangements are taken into consideration: a system with a nonpulsatile pump (a roller pump) and a system with a pulsatile pump (two roller pumps, or one bellows pump). It is demonstrated that, using a pulsatile pump and an optimised pump frequency, it is possible to achieve a reduction in pressure variations as well as flow-velocity variations (with a correspondingly reduced haemolysis rate), and also to achieve an increase in the mean blood flow (comparable to a two-needle system).
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02455305
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