Publication Date:
2008-12-17
Description:
The RNA-binding protein FCA promotes flowering in Arabidopsis. Razem et al. reported that FCA is also a receptor for the phytohormone abscisic acid (ABA). However, we find that FCA does not bind ABA, suggesting that the quality of the proteins assayed and the sensitivity of the ABA-binding assay have led Razem et al. to erroneous conclusions. Because similar assays have been used to characterize other ABA receptors, our results indicate that the ABA-binding properties of these proteins should be carefully re-evaluated and that alternative ABA receptors are likely to be discovered.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Risk, Joanna M -- Macknight, Richard C -- Day, Catherine L -- England -- Nature. 2008 Dec 11;456(7223):E5-6. doi: 10.1038/nature07646.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Biochemistry Department, University of Otago, Dunedin 9054, New Zealand. catherine.day@otago.ac.nz.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19078995" target="_blank"〉PubMed〈/a〉
Keywords:
Abscisic Acid/*metabolism
;
Arabidopsis/*metabolism
;
Arabidopsis Proteins/*metabolism
;
Protein Binding
;
RNA-Binding Proteins/*metabolism
;
mRNA Cleavage and Polyadenylation Factors/metabolism
Print ISSN:
0028-0836
Electronic ISSN:
1476-4687
Topics:
Biology
,
Chemistry and Pharmacology
,
Medicine
,
Natural Sciences in General
,
Physics
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