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  • 1
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1979-04-13
    Description: Melatonin fulfills many of the criteria for classification as a hormone. Until recently it was considered to be elaborated exclusively by pineal organs. Melatonin synthesis by other tissues has been indicated but not demonstrated unequivocally. Trout retinas in a whole-organ culture system in vitro synthesized tritiated melatonin from a substrate containing tritiated serotonin. This raises the possibility that the trout retina is an endocrine organ.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Gern, W A -- Ralph, C L -- New York, N.Y. -- Science. 1979 Apr 13;204(4389):183-4.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/432640" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Culture Techniques ; Melatonin/*biosynthesis ; Retina/*metabolism ; Serotonin/metabolism ; Trout
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 2
    Publication Date: 1980-10-31
    Description: All living and most fossil representatives of the reptilian subclass Archosauria lack pineal bodies. Arrhythmic, low-level, nonpineal melatonin is present, however, in the blood of Alligator mississippiensis. Although pineal bodies have been implicated in circadian phenomena, these results suggest that arrhytmic melatonin in alligators may not be involved incircadian events and indicate that the pineal is not the only source of the hormone melatonin. The evolutionary loss of the pineal in Archosauria occurred during the Mesozoic, and era noted for its seasonal stability. Arrhythmic melatonin titers inalligators and pineal loss in alligators and other archosaurs may be related to Mesozoic seasonal stability.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Roth, J J -- Gern, W A -- Roth, E C -- Ralph, C L -- Jacobson, E -- NS 12257/NS/NINDS NIH HHS/ -- New York, N.Y. -- Science. 1980 Oct 31;210(4469):548-50.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7423204" target="_blank"〉PubMed〈/a〉
    Keywords: Alligators and Crocodiles/*blood ; Animals ; Biological Evolution ; Melatonin/*blood ; Periodicity ; Pineal Gland/physiology ; Radioimmunoassay ; Reptiles/*blood
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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