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  • 1
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Applied Biomaterials 1 (1990), S. 127-136 
    ISSN: 1045-4861
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine , Technology
    Notes: Traditional water permeability evaluation procedures developed for measurement of gross leakage rates of textile prostheses are not adequate for testing the permeability of low-porosity bio-impregnated vascular prostheses. Obtaining reliable water permeability data for these low porosity grafts requires a technique that can accurately assess minor water leakage under the applied pressure. This study proposes an automated method for graft permeability assessment which measures the pressure change inside the graft sample as a function of water loss. The new unit of water permeability defines the pressure gradient at the given initial conditions. The proposed method for evaluating the water permeability of bio-impregnated vascular prostheses provides highly reliable data, is accurate, and excludes human error.
    Additional Material: 6 Ill.
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  • 2
    Electronic Resource
    Electronic Resource
    Hoboken, NJ : Wiley-Blackwell
    Journal of Biomedical Materials Research 3 (1969), S. 645-654 
    ISSN: 0021-9304
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine , Technology
    Notes: Anodic electrolysis of fibrinogen at platinum electrodes causes the formation of fibrin-type structure at potentials below .08 V S.C.E.; at higher potentials denaturation occurs. Coated electron microscope grids were used as electrodes in fibrinogen solutions. When removed and dried these grids contain a protein film which acts as a sampler-substrate for entities which are either in solution or are formed at the electrodes.
    Additional Material: 6 Ill.
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  • 3
    Electronic Resource
    Electronic Resource
    Hoboken, NJ : Wiley-Blackwell
    Journal of Biomedical Materials Research 33 (1996), S. 159-175 
    ISSN: 0021-9304
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine , Technology
    Notes: A simple wear test was investigated for evaluating the wear and damage of material pairs when used in total knee replacement. The test consisted of an axially loaded metallic femoral indentor and a reciprocating ultrahigh molecular weight polyethylene (UHMWPE) flat disk that represented the tibial component. A number of variables were studied including the effect of conformity by varying the radii of the femoral surface, distilled water or serum as a lubricant, different femoral materials, and different types of UHMWPE. In general, the different morphologies of the surface wear of the UHMWPE were similar to those seen on retrieved total knee replacements. Increased conformity with a cylindrical indentor gave a reduced wear rate initially, compared with that of the lower conformity spherical indentor. However, the wear rates were similar subsequent to this initial wearing in phase. Transfer films of UHMWPE were observed on the cobalt-chrome indentors for both serum and distilled water lubrication, although this film was more extensive for distilled water. The lowest wear rate was observed when oxidized zirconium was used on the femoral side, which was attributed to greater wettability, surface hardness, and immunity to oxidative wear. Tests using cobalt-chrome femoral cylinders and different grades of UHMWPE showed different wear rates. Of these PEs, GUR 415 showed less wear than both RCH 1000 and UHMWPE containing numerous fusion defects. For the latter, wear was attributed to a fatigue mechanism, although in most cases it was associated with surface phenomena rather than subsurface cracking. However, in some specimens of UHMWPE subsurface crack propagations occurred with defects. The test method is discussed in relation to its applicability to the evaluation and comparison of bearing materials and surfaces, with particular application to total knee replacements. © 1996 John Wiley & Sons, Inc.
    Additional Material: 13 Ill.
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  • 4
    Electronic Resource
    Electronic Resource
    Hoboken, NJ : Wiley-Blackwell
    Journal of Biomedical Materials Research 8 (1974), S. 245-260 
    ISSN: 0021-9304
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine , Technology
    Notes: The surface replacement hip prosthesis reported represents an attempt to improve upon some aspects of the present design of total hip. The prosthesis comprises a cap fitted over the femoral head and a liner fixed into the socket, both being cemented with methyl methacrylate. The chief advantage of this design is preservation of bone stock. The prostheses were inserted bilaterally into six dogs, and whilst ten joints failed, one case was strikingly successful at two years follow-up. It was concluded that the design showed sufficient advantages over current total hips and that there was sufficient possibility of success in some application, to merit further study.
    Additional Material: 11 Ill.
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  • 5
    Electronic Resource
    Electronic Resource
    Hoboken, NJ : Wiley-Blackwell
    Journal of Biomedical Materials Research 11 (1977), S. 195-210 
    ISSN: 0021-9304
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine , Technology
    Notes: Thirty different test patches of various thin film materials were chronically implanted in the subdural space of cats to determine their suitability as components for proposed neuroprosthetic devices. In particular, materials employed by the microelectronics industry were screened, and reactions were found to be quite dependent on specific formulations or surface preparations of otherwise similar materials. A nonspecific but severe complication of pressure necrosis under thin films that spontaneously roll and curl in vivo was noted.
    Additional Material: 5 Ill.
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  • 6
    Electronic Resource
    Electronic Resource
    Hoboken, NJ : Wiley-Blackwell
    Journal of Biomedical Materials Research 10 (1976), S. 61-76 
    ISSN: 0021-9304
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine , Technology
    Notes: Some of the mechanical properties of regrown canine tendons are compared to those of normal tendons of young and mature animals. Patellar and Achilles tendons from 12 beagle dogs were removed and studied with their bone origin and insertions. Mechanical tests were performed within 24 hr and test conditions simulated the physiological function of the tendon in vivo at room temperature. Specimens were soaked in Ringers solution and mounted in an Instron testing machine with load deflection curves plotted automatically. The parameters used for analysis were load extension, stress relaxation, elastic limit, and strain rate dependence.The regrown tendons in young animals appeared to quickly adjust in dimension and structure so that their properties were not significantly different from those of normal tendons on a load extension basis.The normal tendons were stiffer than regrown ones but the modulus of elasticity increased with age. The Achilles were stiffer than patellar tendons. Cyclic loading with 25 kg did not affect reconstructed tendon models, although some increase in stiffness was noted. The elastic modulus decreased with an increase in ambient temperature and increasing strain rate.
    Additional Material: 9 Ill.
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  • 7
    Electronic Resource
    Electronic Resource
    Hoboken, NJ : Wiley-Blackwell
    Journal of Biomedical Materials Research 43 (1998), S. 162-167 
    ISSN: 0021-9304
    Keywords: guided bone regeneration ; expanded polytetrafluoroethylene (ePTFE) ; cyanoacrylate ; osteopromotion ; osseointegration ; Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine , Technology
    Notes: This study investigated the use of a prototype expanded polytetrafluoroethylene membrane attached to bone with butyl-cyanoacrylate, in facilitating guided bone regeneration into bone defects and around titanium screws in rabbit femora. Two experimental models were used to assess bone growth. The first model investigated two unicortical defects in each femora. The second was bone growth in a 500-μm engineered space around one transcortical titanium screw. In the first model there was a significant increase in bone formation at 1 and 2 months in the membrane groups (p 〈 0.01) as compared to the controls. In the second model the percentage of bone in contact with the implant was significant at 1 and 2 months in the defects covered with membrane compared to the uncovered defects. The uncovered defects had fibrous tissue adherent to the implant continuous with the overlying soft tissue. Our study demonstrated three points: this membrane can be used to increase bone regeneration into defects, this technique allows bone to grow directly around an implant, and butyl-cyanoacrylate can be used in deep soft tissue and bone applications without any apparent deleterious effects. © 1998 John Wiley & Sons, Inc. J Biomed Mater Res (Appl Biomater) 43: 162-167, 1998
    Additional Material: 11 Ill.
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  • 8
    Electronic Resource
    Electronic Resource
    Hoboken, NJ : Wiley-Blackwell
    Journal of Biomedical Materials Research 7 (1973), S. 327-342 
    ISSN: 0021-9304
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine , Technology
    Notes: The two systems for artificial hip joints in use at present are metal-on-metal and metal-on-plastic. There are many variables affecting friction and wear, which include diameter, sphericity, relative geometry of the components, and surface roughness. Tests in a simulating machine incorporated cyclic load and motion. Frictional torque of metal-on-plastic joints increased with diameter; Charnley 22 mm diameter producing lowest friction. For metal-on-metal the contact situation produced variable results, but friction was higher than for the plastic joints. Reciprocating friction machine tests suggested that high molecular weight polyethylene and AP4 polyester gave low friction and wear. Vitallium gave at least three times the friction of the plastic using γ-globulin solution as lubricant; but wear appeared to be much less.
    Additional Material: 10 Ill.
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