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    Electronic Resource
    Chichester : Wiley-Blackwell
    Organic Magnetic Resonance 4 (1972), S. 875-883 
    ISSN: 0030-4921
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: The NMR spectra of a spiro oxirane (1) derivative of codeinone, codeine (2), isocodeine (3), 6-methylcodeine (4) and 6-methylisocodeine (5) were compared. NOE and double-resonance experiments were used to confirm the conformation of 1, and the configuration about C-6 of 6-methylcodeine and 6-methylisocodeine. An interchange of the chemical shifts of the olefinic protons in 1 was noted, as compared with those in all of the other compounds. This interchange could be attributed to the bond anisotropies of the oxirane moiety.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
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