ISSN:
1052-9306
Keywords:
Chemistry
;
Analytical Chemistry and Spectroscopy
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Five children deficient in growth hormone were treated with oxandrolone and human growth hormone. Average nitrogen retained was calculated from nine day balance data. During some balance periods, nitrogen retention was calculated by determination of 15N labeled glycine, as reported in this article. Twenty milligrams of 15N in excess of the natural abundance was administered orally. Urines were collected prior to, as well as after, administration of glycine-15 N and were analyzed for 15N by mass spectrometry. The percentage of 15N ranged up to 0.449% for collection over a 24 hour period, compared with 0.364% from control samples without excess 15N. These 15N data, like those from nitrogen balance, show the stimulating effects of oxandrolone and human growth hormone in the group as a whole.
Additional Material:
3 Tab.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/bms.1200020302
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