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  • Analytical Chemistry and Spectroscopy  (3)
  • Hydroxychloroquine  (1)
  • Polymer and Materials Science  (1)
  • Rat-lung cell  (1)
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  • 1
    Digitale Medien
    Digitale Medien
    Induction of in vivo DNA adducts by 4 industrial by-products in the rat-lung-cell system
    Amsterdam : Elsevier
    Mutation Research/Environmental Mutagenesis and Related Subjects 312 (1994), S. 165-172 
    Details
    ISSN: 0165-1161
    Schlagwort(e): DNA adduct ; Micronucleus ; PAH ; Rat-lung cell ; SCE
    Quelle: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Thema: Biologie , Medizin
    Materialart: Digitale Medien
    URL: http://linkinghub.elsevier.com/retrieve/pii/0165-1161(94)90022-1
    Standort Signatur Erwartet Verfügbarkeit
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  • 2
    Digitale Medien
    Digitale Medien
    Plasma protein binding of the enantiomers of hydroxychloroquine and metabolites (1993)
    Springer
    European journal of clinical pharmacology 44 (1993), S. 481-484 
    Details
    ISSN: 1432-1041
    Schlagwort(e): Hydroxychloroquine ; enantiomers ; protein binding ; metabolites
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Chemie und Pharmazie , Medizin
    Notizen: Summary The in vitro binding of the enantiomers of hydroxychloroquine and its three major metabolites in pooled plasma obtained from four healthy volunteers and the binding of the enantiomers of hydroxychloroquine to purified plasma proteins has been investigated. The plasma protein binding of hydroxychloroquine was found to be stereoselective. The (S)-enantiomer of hydroxychloroquine was 64% bound in plasma, while (R)-hydroxychloroquine was 37% bound. Fifty % of (S)-hydroxychloroquine was bound to a 40 g·l−1 solution of human serum albumin, while only 29% of the (R)-enantiomer was bound. The enantioselectivity of hydroxychloroquine binding was reversed in a 0.7 g·l−1 solution of α1-acid glycoprotein with (R)-hydroxychloroquine being bound to a greater extent than its optical antipode (41% versus 29%). The enantiomers of the metabolites of hydroxychloroquine were bound to a similar extent to plasma and purified plasma proteins. Binding of hydroxychloroquine to plasma and purified proteins was found to be linear over the racemic concentration range of 50 to 1000 ng·ml−1 and hydroxychloroquine metabolite binding to plasma was linear over the range 25 to 500 ng·ml−1.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00315548
    Standort Signatur Erwartet Verfügbarkeit
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  • 3
    Digitale Medien
    Digitale Medien
    Linear polyethylene in a glassy phase: The value of the glass-transition temperature (1979)
    New York : Wiley-Blackwell
    Journal of Polymer Science: Polymer Physics Edition 17 (1979), S. 907-915 
    Details
    ISSN: 0098-1273
    Schlagwort(e): Physics ; Polymer and Materials Science
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie , Physik
    Notizen: Raman spectroscopy, x-ray diffraction, and thermal analysis are used to investigate the structure of linear high-density polyethylene rapidly quenched from the melt to cryogenic temperatures. All the results point to the production of a glassy phase which crystallizes when heated above 170 K.
    Zusätzliches Material: 5 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/pol.1979.180170601
    Standort Signatur Erwartet Verfügbarkeit
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  • 4
    Digitale Medien
    Digitale Medien
    Use of optical fibres in Raman spectroscopy (1988)
    Chichester [u.a.] : Wiley-Blackwell
    Journal of Raman Spectroscopy 19 (1988), S. 413-418 
    Details
    ISSN: 0377-0486
    Schlagwort(e): Chemistry ; Analytical Chemistry and Spectroscopy
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie , Physik
    Notizen: A detailed study of the parameters governing the design of an optical fibre system for use in Raman spectroscopy is described. The results have led to the design and construction of a flexible fibre optic remote sampling system which is easily adaptable for use on most commercial instruments. A variety of samples were used to evaluate the performance of the system and have been classified in terms of the efficiency of the new technique relative to more conventional methods of excitation and collection.
    Zusätzliches Material: 5 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/jrs.1250190607
    Standort Signatur Erwartet Verfügbarkeit
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  • 5
    Digitale Medien
    Digitale Medien
    A new multichannel Raman optical activity instrument (1987)
    Chichester [u.a.] : Wiley-Blackwell
    Journal of Raman Spectroscopy 18 (1987), S. 281-287 
    Details
    ISSN: 0377-0486
    Schlagwort(e): Chemistry ; Analytical Chemistry and Spectroscopy
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie , Physik
    Notizen: A fully computer-controlled Raman optical activity spectrometer equipped with an intensified diode array detector is described. Despite using a conventional single-lens light collection system for simplicity, both polarized and depolarized Raman optical activity spectra can be obtained rapidly and routinely. A novel double grating spectrograph design permits good spectra to be obtained down to 50 cm-1 in liquids. Natural spectra of the chiral samples (-)-α-pinene and (+)-methylcyclohexanone and magnetic spectra of iridium (IV) hexachloride are presented.
    Zusätzliches Material: 7 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/jrs.1250180410
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  • 6
    Digitale Medien
    Digitale Medien
    An observation of resonance Raman in the near-infrared (1990)
    Chichester [u.a.] : Wiley-Blackwell
    Journal of Raman Spectroscopy 21 (1990), S. 699-702 
    Details
    ISSN: 0377-0486
    Schlagwort(e): Chemistry ; Analytical Chemistry and Spectroscopy
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie , Physik
    Notizen: The NIR FT Raman spectrum of bacteriorhodopsin is reported. By comparison with previously published spectra it appears that there is some degree of resonance enhancement. Also reported is the spectrum of a sample of blue dyed cotton. Resonance enhancement is proposed to explain strong features in the spectrum not present in either undyed or red dyed material.
    Zusätzliches Material: 3 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/jrs.1250211011
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