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Fungitoxicity ofm-fluorophenylalanine-containing peptides towardsPythium ultimum (1989)

Young, D. H. ; Mehta, R. J.

Springer

Cellular and molecular life sciences 45 (1989), S. 325-327

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ISSN: 1420-9071

Keywords: Amino acid transport ; fluorophenylalanine ; peptide transport ; Pythium ultimum

Source: Springer Online Journal Archives 1860-2000

Topics: Biology , Medicine

Notes: Summary The tripeptide L-m-fluorophenylalanyl-L-alanyl-L-alanine was much more fungitoxic towardsPythium ultimum than the dipeptide L-m-fluorophenylalanyl-L-alanine orm-fluorophenylalanine. The fungitoxicity of the tripeptide was reduced by L-alanyl peptides and phenylalanine, but not by other amino acids. In contrast, the fungitoxicity ofm-fluorophenylalanine was unaffected by peptides, and was antagonized by several amino acids. These results suggest the effective delivery ofm-fluorophenylalanine into the cell by a tripeptide carrier.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF01957464

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