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  • Weibull distribution function  (2)
  • Amino acid sequence  (1)
  • Crotalid snakes  (1)
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  • 1
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Biochimica et Biophysica Acta (BBA)/Gene Structure and Expression 1216 (1993), S. 332-334 
    ISSN: 0167-4781
    Keywords: (Chicken liver) ; Amino acid sequence ; Clone ; Gluthatione S-transferase ; Nucleotide sequence
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Medicine , Physics
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1572-8935
    Keywords: Fatigue behavior ; AS-4/PEEK ; Composites ; Weibull distribution function ; Tension-tension ; Surface temperature change
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Abstract Fatigue behavior of carbon fiber reinforced poly etheretherketone (PEEK) laminated composite was investigated. The [±45]4s AS-4/PEEK laminated composites under static tensile measurement at various test temperatures were conducted. Three tension-tension fatigue loading frequencies, 1 Hz, 5 Hz and 10 Hz, were selected to study the effect of frequency on the fatigue behavior of [±45]4s AS-4/PEEK laminate. The survival probability of experimental fatigue life data under different stress amplitude tests were estimated and analyzed by the median rank order-statistic cumulative-distribution function and the Weibull distribution function. The S-N curves at different fatigue loading frequencies exhibited a trend of two-segment straight line curves. The increase in surface temperature of specimens was found and the thermal stress history was also investigated by thermo-image techniques during fatigue life testing. The fatigue failure mechanism was investigated by X-ray radiography.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1572-8935
    Keywords: Fatigue behavior ; C.F./PEEK ; Composites ; Weibull distribution function ; Hygrothermal ; Impact
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Abstract The hygrothermal effects on the fatigue behavior of the Carbon/PEEK laminated composites before and after impact damage were examined in this study. The [0/45/90/-45]2s AS-4/PEEK laminated composites were immersed in 80°C hot water for 45, 90 and 200 days,and subjected to falling weight impact with an energy of 8.58 J and then immersed in 80°C hot water for 45 days. It was found that the tensile strength of AS-4/PEEK laminated composites decreased with the increase of exposure period. The injured AS-4/PEEK composites were subjected to a static load and a tensiontension fatigue load at various levels of stress amplitudes. The effect of stress amplitude on the fatigue life was studied. The experimental fatigue life under different stress amplitude tests were estimated by the median rank order statistic cumulative distribution function. Then,the fitting curves for estimated data were analyzed by the Weibull distribution function. The S-N curves for a series of cyclic loads at various survival probabilities were presented. The damage behaviors of composites after fatigue load test were also investigated by scanning electron microscope(SEM). Results indicated the fatigue lives of immersed specimens were shorter than those without hygrothermal effect, the impact damage affects the fatigue life of composite significantly.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1573-4943
    Keywords: Crotalid snakes ; fibrinogenases ; factors IX/X-binding proteins ; thrombin-like serine proteases ; botrocetin ; platelet agglutination ; von Willebrand factor
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract One novel venom factor was isolated and purified from the venom of Taiwan habu (Trimeresurus mucrosquamatus) using two consecutive anion-exchange and gel-filtration chromatographies followed by cation-exchange HPLC. Further characterization of the purified protein indicated that it lacks the proteolytic activity toward fibrinogen molecules, suggesting that this protein factor does not belong to the familes of metalloproteinases and thrombin-like serine proteases commonly found in the crude venoms of various crotalid snakes. The purified protein exists as a native dimeric protein of 26 kDa, consisting of two closely similar subunits of 16 and 13 kDa, held together by disulfide linkage. N-Terminal sequence analysis revealed that both chains are homologous to each other at the N-terminal fragment and also similar to the factors IX/X-binding protein isolated fromTrimeresurus flavoviridis and botrocetin fromBothrops jararaca. This study points to the existence of one new two-chain venom factor without fibrinogenase activity from Taiwan habu, which, in contrast to botrocetin, promotes platelet agglutination even in the absence of von Willebrand factor. Unlike factors IX/X-binding proteins, it did not show affinity to coagulation factors IX and X in the presence of Ca2+ ion. It also shows no inhibition on thrombin, in contrast with bothrojaracin, a thrombin inhibitor isolated fromBothrops jararaca venom. We have therefore named this novel venom factortrimecetin to distinguish it from some structurally related venom factors present in various crotalid and viperid snakes.
    Type of Medium: Electronic Resource
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